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New treatment option for Postmenopausal Symptoms
Official title Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
ClinicalTrials.gov ID: NCT06030388
What this study is testing
- What it's testing
- The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptoms (hot flushes) in postmenopausal women. The main question it aims to answer is the effect of 15 weeks of strength training vs high intensity aerobic training vs unchanged physical activity on frequency and severity of hot flushes.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 45 and older, women only
You may be able to join if
- Postmenopausal women (one of: ≥ 12 months since last menstruation; amenorrhea due to intrauterine device or hysterectomy and Follicle Stimulating...
- ≥ 28 moderate to severe hot flushes per week during a 2-week screening period, registered through a daily VMS diary;
- Age ≥45 years;
- Physical ability to participate in strength training or high intensity aerobic exercise for 60 minutes, 3 times/week during 15 weeks;
- Understand Swedish orally and in writing
You likely can't join if
- Regular physical activity \>30 minutes per week of vigorous intensity or ≥150 minutes of moderate intensity or combined activities representing...
- Use of systemic menopausal hormone therapy the last 2 months;
- Use of natural preparations such as herbal preparations for VMS, or other medications for VMS the last 2 months;
- Capillary hemoglobin \<110 g/l;
- Blood pressure \>160 mmHg systolic or \>100 mmHg diastolic;
- Unstable medical condition with a potential to affect VMS (like unregulated thyroid disease);
See the full eligibility criteria
- Postmenopausal women (one of: ≥ 12 months since last menstruation; amenorrhea due to intrauterine device or hysterectomy and Follicle Stimulating Hormone (FSH) \>30 mIU/ml; bilateral oophorectomy; induced menopause due...
- ≥ 28 moderate to severe hot flushes per week during a 2-week screening period, registered through a daily VMS diary;
- Age ≥45 years;
- Physical ability to participate in strength training or high intensity aerobic exercise for 60 minutes, 3 times/week during 15 weeks;
- Understand Swedish orally and in writing
- Regular physical activity \>30 minutes per week of vigorous intensity or ≥150 minutes of moderate intensity or combined activities representing maximum 150 minutes of moderate intensity;
- Use of systemic menopausal hormone therapy the last 2 months;
- Use of natural preparations such as herbal preparations for VMS, or other medications for VMS the last 2 months;
- Capillary hemoglobin \<110 g/l;
- Blood pressure \>160 mmHg systolic or \>100 mmHg diastolic;
- Unstable medical condition with a potential to affect VMS (like unregulated thyroid disease);
- Medical condition that by a physician is judged not appropriate (because of potential to affect VMS or risk of injury with vigorous exercise)
The study team makes the final eligibility decision.
Where it's taking place
- Kalmar, Sweden
- Linköping, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 45 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kalmar, Sweden; Linköping, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.