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Official title Melanin and Dermal Uptake of Thirdhand Cigarette Smoke
ClinicalTrials.gov ID: NCT06020248
What this study is testing
- What it's testing
- This is a pilot study of the effects of dermal melanin on dermal uptake and retention of nicotine. The initial hypothesis is that higher levels of dermal melanin will correlate with lower uptake and longer retention of nicotine in the skin and body.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50. Healthy volunteers may be eligible.
You may be able to join if
- Adult nonsmoker
- Aged 18-50
- Skin reflectance scores below 150 or above 249 using the Mexameter 18 instrument
- Healthy on the basis of medical history
- Systolic blood pressure \<150
You likely can't join if
- Dermal skin reflectance score between 150 and 249, as measured by the Mexameter 18 instrument.
- Positive SARS-CoV-2 antibody test
- Age 18 \ 50
- Physician diagnosis of asthma, heart disease, hypertension, thyroid disease, diabetes, renal or liver impairment or glaucoma.
- Unstable psychiatric condition (such as current major depression, history of schizophrenia or bipolar disorder) or current use of more than two...
- Systolic blood pressure greater than or equal to 150
See the full eligibility criteria
- Adult nonsmoker
- Aged 18-50
- Skin reflectance scores below 150 or above 249 using the Mexameter 18 instrument
- Healthy on the basis of medical history
- Systolic blood pressure \<150
- Diastolic blood pressure \<100
- C-reactive protein \<3.1 mg/ml
- Liver function (AST and ALT) in normal ranges
- kidney function (BUN) in normal ranges
- LDL\<131
- Blood glucose \<110
- Not exposed to tobacco SHS.
- Dermal skin reflectance score between 150 and 249, as measured by the Mexameter 18 instrument.
- Positive SARS-CoV-2 antibody test
- Age 18 \ 50
- Physician diagnosis of asthma, heart disease, hypertension, thyroid disease, diabetes, renal or liver impairment or glaucoma.
- Unstable psychiatric condition (such as current major depression, history of schizophrenia or bipolar disorder) or current use of more than two psychiatric medications
- Systolic blood pressure greater than or equal to 150
- Diastolic blood pressure greater than or equal to 100
- Blood glucose greater than or equal to 110
- LDL greater than or equal to130
- Pregnancy or breastfeeding (by urine hCG and/or history)
- Alcohol or illicit drug dependence within the past 5 years
- BMI \> 35 and \< 18
- Current illicit drug use (by history or urine test)
- More than 1 pack year smoking history
- Ever a daily marijuana smoker
- Smoked anything within the last 3 months
- Unable to hold allergy or other OTC medicines
- Occupational exposure to smoke, dusts OR fumes
- Concurrent participation in another clinical trial
- Unable to communicate in English
- No social security number
The study team makes the final eligibility decision.
Where it's taking place
- San Francisco, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include San Francisco, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.