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New treatment option for Acute Respiratory Distress Syndrome
Official title Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome
ClinicalTrials.gov ID: NCT06013319
What this study is testing
What is Esmolol?
Esmolol is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for acute respiratory distress syndrome.
Also referred to as Esmolol hydrochloride injection.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Acute respiratory distress syndrome (ARDS) is a clinical syndrome caused by intrapulmonary and/or extrapulmonary causes, characterized by intractable hypoxemia. Studies have shown that the sympathetic nervous system is over-activated in patients with acute respiratory distress syndrome.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Meeting the 2012 Berlin diagnostic criteria for acute respiratory distress syndrome;
- Aged between 18-65 years (inclusive);
- 95 times/min ≤ heart rate ≤120 times/min;
- The patient needs to undergo endotracheal intubation mechanical ventilation after condition assessment;
- Obtain the informed consent of the patient or his legal representative.
You likely can't join if
- Bradycardia and second degree or more atrioventricular block;
- Long-term use of beta-blockers;
- Combined with emphysema, asthma and other β-blocker contraindicated diseases;
- Cardiac insufficiency (NYHA grade Ⅲ or Ⅳ);
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Jinan, Shandong, China
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Jinan, Shandong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.