Recruiting PHASE4 Postoperative Delirium

Compares treatment options for Postoperative Delirium

Official title The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium

ClinicalTrials.gov ID: NCT05990790

What this study is testing

What is Desflurane?

Desflurane is an investigational medicine, being studied as a potential treatment for postoperative delirium.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
Patients over the age of 65 years are at increased risk for developing delirium after noncardiac surgeries, resulting in increased morbidity and mortality. The prevention of postoperative delirium has been classified as a public health priority.
  • Phase 4: studies an already-approved treatment
  • Which group you join is decided by chance.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 65 and older

You may be able to join if

  • Provide written informed consent
  • ≥65 years of age
  • Scheduled for elective major noncardiac surgery with estimated time of surgery ≥ 2 hours

You likely can't join if

  • Patients undergoing emergency surgery
  • BMI \> 45 kg/m\^2
  • History of diagnosed dementia
  • Language, vision, or hearing impairments that may compromise cognitive assessments
  • History of malignant hyperthermia
  • History of structural muscle disease
See the full eligibility criteria
Who can join
  • Provide written informed consent
  • ≥65 years of age
  • Scheduled for elective major noncardiac surgery with estimated time of surgery ≥ 2 hours
What rules you out
  • Patients undergoing emergency surgery
  • BMI \> 45 kg/m\^2
  • History of diagnosed dementia
  • Language, vision, or hearing impairments that may compromise cognitive assessments
  • History of malignant hyperthermia
  • History of structural muscle disease
  • History of organ transplantation (kidney, liver, lung, heart)
  • Patients undergoing hyperthermic intraperitoneal chemotherapy
  • ICU patients undergoing surgery

The study team makes the final eligibility decision.

Where it's taking place

  • Innsbruck, Austria
  • Vienna, Austria

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 65 years and older. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Innsbruck, Austria; Vienna, Austria. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.