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New treatment option for Skin Wound
Official title Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
ClinicalTrials.gov ID: NCT05984628
What this study is testing
- What it's testing
- The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds. The study aims to answer the following main questions: Question 1: Does hUCMSC therapy improve the healing quality and speed of donor site wounds in comparison to standard treatment?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Patients between 18 and 60 years old with extensive scars, large benign tumors, or fresh wounds on the body surface.
- Patients who undergo medium-thickness skin graft surgery (donor site can be from the thigh, abdomen, or back).
- Participants who have a thorough understanding of the study objectives, significance, implementation plan, potential benefits, risks involved...
You likely can't join if
- Participants who meet any of the following criteria are not suitable for inclusion:
- Hypertension, hypotension, heart disease (including history of myocardial ischemia, coronary heart disease, myocarditis).
- Liver or kidney dysfunction.
- Infectious diseases (including viral hepatitis, syphilis, HIV/AIDS, etc.).
- Venous thrombosis, thoracic or abdominal aortic aneurysm, aortic dissection.
- Blood disorders (abnormal coagulation function, anemia, leukemia, polycythemia vera, aplastic anemia, etc.).
See the full eligibility criteria
- Patients between 18 and 60 years old with extensive scars, large benign tumors, or fresh wounds on the body surface.
- Patients who undergo medium-thickness skin graft surgery (donor site can be from the thigh, abdomen, or back).
- Participants who have a thorough understanding of the study objectives, significance, implementation plan, potential benefits, risks involved, measures to address risks, and the rights and obligations of the people...
- Participants who meet any of the following criteria are not suitable for inclusion:
- Hypertension, hypotension, heart disease (including history of myocardial ischemia, coronary heart disease, myocarditis).
- Liver or kidney dysfunction.
- Infectious diseases (including viral hepatitis, syphilis, HIV/AIDS, etc.).
- Venous thrombosis, thoracic or abdominal aortic aneurysm, aortic dissection.
- Blood disorders (abnormal coagulation function, anemia, leukemia, polycythemia vera, aplastic anemia, etc.).
- Allergic conditions (urticaria, bronchial asthma, history of allergic reactions to two or more drugs or foods).
- Respiratory system diseases (chronic bronchitis, emphysema, bronchiectasis, respiratory failure, chronic obstructive pulmonary disease, interstitial pneumonia).
- Digestive system diseases (severe gastric or duodenal ulcers, chronic gastritis, chronic pancreatitis).
- Urinary system diseases (chronic urinary tract infections, nephritis, nephrotic syndrome).
- Endocrine system diseases (hyperthyroidism, diabetes, acromegaly, pituitary diseases, adrenal diseases, diabetes insipidus).
- Organic neurological disorders or psychiatric illnesses (encephalitis, sequelae of traumatic brain injury, epilepsy, schizophrenia, hysteria, depression, severe insomnia, neurasthenia).
- Chronic skin diseases (especially infectious, allergic, and inflammatory systemic skin diseases, such as extensive eczema, pemphigus, pemphigoid).
- Autoimmune diseases and collagen diseases (such as systemic lupus erythematosus, dermatomyositis, scleroderma).
- History of long-term smoking, alcohol abuse, or drug addiction.
- History of major surgeries (such as gastric, lung, splenic, renal, or liver resection).
- History of other significant malignant tumors.
- Blood donation or organ transplantation within the past 5 years.
- Pregnancy, lactation, menstrual period, or within 1 year after termination of pregnancy.
- Previous circumstances of being rejected for voluntary blood donation.
- Other situations deemed unsuitable for participation in this study by the investigators.
The study team makes the final eligibility decision.
Where it's taking place
- Fujian, Fuzhou, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Fujian, Fuzhou, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.