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New treatment option for Cataract Surgery
Official title Remimazolam for Cataract Surgery
ClinicalTrials.gov ID: NCT05980117
What this study is testing
What is Remimazolam?
Remimazolam is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for cataract surgery.
Also referred to as Byfavo.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this study is to assess any post operative cognitive changes following benzodiazepine administration during cataract surgery. The investigators will compare effects of Midazolam vs.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 and older
You may be able to join if
- Adult patients age \> 65 years undergoing first eye cataract surgery under local topical anesthesia at the University of California, Los Angeles...
- Both male and female patients
- American Society of Anesthesiologists Class 2, 3, and 4.
You likely can't join if
- Patients who are unable to consent for the study
- Patients who are unable to cooperate with the cognitive assessment such as patients with significant visual, auditory, language or other impairment.
- Patients who are unable to understand simple English commands.
- Patients who do not wish to have benzodiazepine medication during surgery
- Patients with a history of severe hypersensitivity reaction to dextran 40 or products containing dextran 40.
- Patients with chronic pain on opiates.
See the full eligibility criteria
- Adult patients age \> 65 years undergoing first eye cataract surgery under local topical anesthesia at the University of California, Los Angeles (UCLA).
- Both male and female patients
- American Society of Anesthesiologists Class 2, 3, and 4.
- Patients who are unable to consent for the study
- Patients who are unable to cooperate with the cognitive assessment such as patients with significant visual, auditory, language or other impairment.
- Patients who are unable to understand simple English commands.
- Patients who do not wish to have benzodiazepine medication during surgery
- Patients with a history of severe hypersensitivity reaction to dextran 40 or products containing dextran 40.
- Patients with chronic pain on opiates.
- Patients with a history of drug, alcohol abuse/dependence.
- Patients with BMI \> 40.
- Patients with obstructive sleep apnea (moderate to severe).
The study team makes the final eligibility decision.
Where it's taking place
- Los Angeles, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Los Angeles, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.