BridgeMD
New treatment option for Vitamin D Deficiency
Official title Early Vitamin D3 Supplementation for Critically Ill Patients
ClinicalTrials.gov ID: NCT05937789
What this study is testing
- What it's testing
- There are no clear international guidelines for dosing vitamin D based on deficiency severity. Therefore, a new clinical trial is needed to evaluate the benefits of early vitamin D supplementation in maintaining sufficient levels for critically ill patients.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- ≥18-year-old critically ill patient.
- ICU admission \< 24 hours.
- Baseline 25(OH)D levels within 24 hours of ICU admission \< 20 ng/mL.
- Expected ICU length of stay ≥ 72 hours.
You likely can't join if
- Hypercalcemia (ie. total serum calcium levels \> 2.6 mmol/L).
- Disorders affecting serum 25(OH)D levels, calcium metabolism, or bone metabolism (eg, parathyroid disease, rickets, or severe cirrhosis [Child C]).
- Having received high-dose vitamin D3 therapy (ie. \> 2,000 IU daily or a single dose of ≥ 10,000 IU) within the past four weeks.
- Active COVID-19 at ICU admission.
- Organ transplant.
- Having had tuberculosis, sarcoidosis or kidney stones within the past year.
See the full eligibility criteria
- ≥18-year-old critically ill patient.
- ICU admission \< 24 hours.
- Baseline 25(OH)D levels within 24 hours of ICU admission \< 20 ng/mL.
- Expected ICU length of stay ≥ 72 hours.
- Hypercalcemia (ie. total serum calcium levels \> 2.6 mmol/L).
- Disorders affecting serum 25(OH)D levels, calcium metabolism, or bone metabolism (eg, parathyroid disease, rickets, or severe cirrhosis [Child C]).
- Having received high-dose vitamin D3 therapy (ie. \> 2,000 IU daily or a single dose of ≥ 10,000 IU) within the past four weeks.
- Active COVID-19 at ICU admission.
- Organ transplant.
- Having had tuberculosis, sarcoidosis or kidney stones within the past year.
- Having renal dialysis, continuous kidney replacement therapy (CKRT), acute kidney injury (AKI).
- Having ICU admission within the past three months.
- Non-native-speaking patients and their families
- Pregnant women.
The study team makes the final eligibility decision.
Where it's taking place
- Taipei, Taiwan
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taipei, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.