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Compares treatment options for Intradialytic Hypotension
Official title Improved Hemodynamic Tolerance of Intermittent Hemodialysis Sessions in Intensive Care Unite Using Citrate- vs Acetate-based Dialysate
ClinicalTrials.gov ID: NCT05936710
What this study is testing
- What it's testing
- During intermittent hemodialysis (IHD), the occurrence of intradialytic hemodynamic instability (IHI) is frequent in ICU and impacted morbidity and mortality. Bicarbonate dialysate buffer improves hemodynamic tolerance compared to acetate dialysate buffer.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patient ≥ 18 years old
- Patient hospitalized in an intensive care unit
- Patient with acute renal failure defined by a KDIGO stage ≥ 1 and suspected non-obstructive
- Patient at risk of per dialytic hypotension (capillary refill time ≥ 3 seconds and/or cardiovascular SOFA ≥ 1 and/or lactatemia \> 2mmol/L)
- Indication for Extra Renal Replacement Therapy with IHD.
You likely can't join if
- Pregnant or breastfeeding woman
- Known chronic renal insufficiency of any stage
- Cardio-renal and hepato renal syndrome
- Unstable hemodynamic state: refractory shock
- Patient included in another treatment study likely to modify the hemodynamic state
- Patient deprived of liberty
See the full eligibility criteria
- Patient ≥ 18 years old
- Patient hospitalized in an intensive care unit
- Patient with acute renal failure defined by a KDIGO stage ≥ 1 and suspected non-obstructive
- Patient at risk of per dialytic hypotension (capillary refill time ≥ 3 seconds and/or cardiovascular SOFA ≥ 1 and/or lactatemia \> 2mmol/L)
- Indication for Extra Renal Replacement Therapy with IHD.
- Pregnant or breastfeeding woman
- Known chronic renal insufficiency of any stage
- Cardio-renal and hepato renal syndrome
- Unstable hemodynamic state: refractory shock
- Patient included in another treatment study likely to modify the hemodynamic state
- Patient deprived of liberty
- Patient under guardianship or curatorship
- Patient not affiliated to a social security system
The study team makes the final eligibility decision.
Where it's taking place
- Béthune, France
- Caen, France
- Dijon, France
- Nancy, France
- Rouen, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Béthune, France; Caen, France; Dijon, France; Nancy, France; Rouen, France. Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.