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New treatment option for Motivation
Official title MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants
ClinicalTrials.gov ID: NCT05929898
What this study is testing
- What it's testing
- The purpose of this research study is to understand how healthy individuals self-regulate motivation by observing brain activity using magnetic resonance imaging (MRI).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Age between 18 and 45 years
- Right-handed
- In good general health
You likely can't join if
- Current or diagnosis within past six months of an DSM-V Axis I or Axis II disorder (self-reported)
- CES-D score of 20 or higher (indicating significant current depression symptoms)
- Current or past six month use of prescription medications indicated for psychiatric conditions (e.g.,depression, anxiety)
- Current serious medical illness (self-reported)
- Head injury resulting in loss of consciousness
- For participants age \> 59 years, a total scaled score \< 8 on the Dementia Rating Scale-2.
See the full eligibility criteria
- Age between 18 and 45 years
- Right-handed
- In good general health
- Current or diagnosis within past six months of an DSM-V Axis I or Axis II disorder (self-reported)
- CES-D score of 20 or higher (indicating significant current depression symptoms)
- Current or past six month use of prescription medications indicated for psychiatric conditions (e.g.,depression, anxiety)
- Current serious medical illness (self-reported)
- Head injury resulting in loss of consciousness
- For participants age \> 59 years, a total scaled score \< 8 on the Dementia Rating Scale-2.
- A clinically-defined neurological disorder including, but not limited to:
- Any condition likely to be associated with increased intracranial pressure
- Space occupying brain lesion
- History of stroke
- Transient ischemic attack within two years
- Cerebral aneurysm
- Dementia
- Mini Mental Status Exam (MMSE) score of \<24
- Parkinson's disease
- Huntington's disease
- Multiple sclerosis
- Presence of cochlear implants or other implanted electronic devices or non-removable metal (e.g., non-removable piercing, IUD)
- History of an eye injury involving metal. Participants who worked with metal may be allowed to participate on a case-by-case basis with prior written approval from BIAC.
- Claustrophobia or unwillingness to tolerate the confinement associated with being in the MRI scanner.
- Weight of more than 250 pounds
The study team makes the final eligibility decision.
Where it's taking place
- Durham, North Carolina, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Durham, North Carolina, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.