BridgeMD
New treatment option for Alcohol Use Disorder
Official title Impulsivity Domains and Subjective Response
ClinicalTrials.gov ID: NCT05929677
What this study is testing
What is Alcohol?
Alcohol is an investigational medicine, given as an once-daily infusion into a vein, being studied as a potential treatment for alcohol use disorder.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Findings from this project will determine the relationship between two vulnerability factors for Alcohol Use Disorder (AUD) in young adults: impulsivity and subjective response to alcohol. The results will identify badly needed, novel targets for prevention and treatment efforts to simultaneously reduce impulsivity and subjective responses in at-risk young adults.
- Phase 1: an early, usually small safety study
- Time commitment: about 2 years
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 25. Healthy volunteers may be eligible.
You may be able to join if
- 21-25 years old
- Report drinking to an estimated BAC \> .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
- Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
- Fluency in English
You likely can't join if
- Any serious medical problems (e.g., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, and gastrointestinal disorders)
- Body weight \ 210 pounds
- Axis I psychiatric disorders including substance use disorder other than mild or moderate alcohol or mild cannabis use disorder
- Current alcohol withdrawal or history of medically-assisted detoxification
- Two positive breath alcohol concentration (BrAC) readings (i.e., \> 0.00%) at an in-person screening appointment or experimental session
- Positive urine screen for illegal drugs other than cannabis
See the full eligibility criteria
- 21-25 years old
- Report drinking to an estimated BAC \> .08% at least once in the past 30 days based on responses on the Timeline Followback (TLFB)
- Report drinking at least twice weekly in the past 30 days based on responses on the TLFB
- Fluency in English
- Any serious medical problems (e.g., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, and gastrointestinal disorders)
- Body weight \ 210 pounds
- Axis I psychiatric disorders including substance use disorder other than mild or moderate alcohol or mild cannabis use disorder
- Current alcohol withdrawal or history of medically-assisted detoxification
- Two positive breath alcohol concentration (BrAC) readings (i.e., \> 0.00%) at an in-person screening appointment or experimental session
- Positive urine screen for illegal drugs other than cannabis
- Currently seeking or past-12-month history of inpatient or intensive treatment for addictive behaviors
- Current psychotropic medication use or receipt of a prescription for these medications in the past 30 days
- Psychosis or other psychiatric disability
- Pregnancy, nursing or lack of reliable birth control use for women
- Report smoking \> 5 cigarettes per day (to avoid acute nicotine effects or withdrawal during experimental sessions)
The study team makes the final eligibility decision.
Where it's taking place
- Boston, Massachusetts, United States
- Columbus, Ohio, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 2 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 25 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Boston, Massachusetts, United States; Columbus, Ohio, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.