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New treatment option for Helicobacter Pylori Infection
Official title A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
ClinicalTrials.gov ID: NCT05926804
What this study is testing
What is Lansoprazole?
Lansoprazole is an investigational medicine, being studied as a potential treatment for helicobacter pylori infection.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Gastric cancer remains a global health problem, and Chile has one of the highest GC mortality rates in the region. Helicobacter pylori (H.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 14 to 18. Healthy volunteers may be eligible.
You may be able to join if
- Healthy teenagers 14-18 years of age from Colina, Temuco or Coyhaique
- At least one responsible adult family member accessible for phone contact.
- Persistent H. pylori infection determined by at least 2 positive UBT tests in a 3 months period (except for Non-infected Controls)
You likely can't join if
- Teenagers not consenting to treatment will be invited to continue as non-treated controls.
- Known allergy to any of the antimicrobials used in the trial protocol (except for Non-infected Controls)
- Signs/symptoms compatible with organic abdominal pain according to Rome IV criteria: persistent right upper or right lower quadrant pain, dysphagia...
- Prior eradication therapy
- Antimicrobial course received during the previous month (at least 3 days of treatment at appropriate dosing, children meeting this criteria can be...
- Pregnancy
See the full eligibility criteria
- Healthy teenagers 14-18 years of age from Colina, Temuco or Coyhaique
- At least one responsible adult family member accessible for phone contact.
- Persistent H. pylori infection determined by at least 2 positive UBT tests in a 3 months period (except for Non-infected Controls)
- Teenagers not consenting to treatment will be invited to continue as non-treated controls.
- Known allergy to any of the antimicrobials used in the trial protocol (except for Non-infected Controls)
- Signs/symptoms compatible with organic abdominal pain according to Rome IV criteria: persistent right upper or right lower quadrant pain, dysphagia, odynophagia, persistent vomiting, gastrointestinal blood loss...
- Prior eradication therapy
- Antimicrobial course received during the previous month (at least 3 days of treatment at appropriate dosing, children meeting this criteria can be included at a later stage)
- Pregnancy
- Use of immunosuppressive or biologic drugs
- Children deemed "not healthy" after review of the questionnaire by study physician
The study team makes the final eligibility decision.
Where it's taking place
- Coyhaique, Chile
- Santiago, Chile
- Temuco, Chile
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 14 years to 18 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Coyhaique, Chile; Santiago, Chile; Temuco, Chile. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.