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New treatment option for Aging
Official title C-Protein in Fatigue and Aging
ClinicalTrials.gov ID: NCT05926219
What this study is testing
- What it's testing
- This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80. Healthy volunteers may be eligible.
You may be able to join if
- Adults between the ages 18-35 or 65-80 years
- Healthy by self-report
- Willing to participate in all aspects of the study design including muscle biopsy, unilateral exercise, and physical activity monitoring
- Fluent in English (due to lack of translation services, it is not practical to conduct the study using a language other than English).
You likely can't join if
- Orthopaedic limitation (severe knee osteoarthritis, prior joint replacement, etc.).
- Volunteer has dementia or related mental issues that potentially put the subject at risk as determined by prior diagnosis.
- Volunteer has known untreated endocrine disease (hypo/hyper thyroidism, Addison's Disease or Cushing's syndrome, etc.)
- Volunteer has untreated/poorly-controlled hypertension (stage 2, per American College of Cardiology [\>140/90 mmHg]).
- Volunteer has significant heart, liver, kidney or respiratory disease.
- Volunteer has diabetes (insulin dependent or non-insulin dependent).
See the full eligibility criteria
- Adults between the ages 18-35 or 65-80 years
- Healthy by self-report
- Willing to participate in all aspects of the study design including muscle biopsy, unilateral exercise, and physical activity monitoring
- Fluent in English (due to lack of translation services, it is not practical to conduct the study using a language other than English).
- Orthopaedic limitation (severe knee osteoarthritis, prior joint replacement, etc.).
- Volunteer has dementia or related mental issues that potentially put the subject at risk as determined by prior diagnosis.
- Volunteer has known untreated endocrine disease (hypo/hyper thyroidism, Addison's Disease or Cushing's syndrome, etc.)
- Volunteer has untreated/poorly-controlled hypertension (stage 2, per American College of Cardiology [\>140/90 mmHg]).
- Volunteer has significant heart, liver, kidney or respiratory disease.
- Volunteer has diabetes (insulin dependent or non-insulin dependent).
- Volunteer has known coagulopathies.
- Volunteer has taken anabolic steroids in the prior six months.
- Volunteer has received treatment for cancer (other than effective Mohs Surgery for successful removal of basal cell or squamous cell carcinomas)
- Unexpected weight loss \>5kg is last 12 months
- Volunteer is an active smoker or quit within the last year.
- Volunteer has known current alcohol or drug use disorder (AUD; defined as binge drinking of \>4 days in the last month. Binge drinking is \>5 drinks for men and \>4 drinks for women, per occasion). Or, if a volunteer...
- Volunteer has a diagnosed neuromuscular disorder.
- Volunteer has allergy to lidocaine.
The study team makes the final eligibility decision.
Where it's taking place
- Eugene, Oregon, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Eugene, Oregon, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.