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New treatment option for Major Depressive Disorder
Official title Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway
ClinicalTrials.gov ID: NCT05913960
What this study is testing
- What it's testing
- Major depressive disorder(MDD) is a complex and heterogeneous mental disorder. Repeated transcranial magnetic stimulation (rTMS), as a non-invasive neuroregulatory technique, has shown a promising function in the treatment of depression.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Sign a written informed consent to participate in the trial and receive treatment;
- Major depressive disorder diagnosis;
- Hamilton depression scale (HAMD - 24) 24 total score 20 points or more;
- First episode or recurrence of depression patients, not taking psychiatric drugs;
- The han nationality, right-handed;
You likely can't join if
- Other organic mental disorders and mental retardation and other severe mental disorders;
- Infection, trauma, and autoimmune diseases or other possible interference test evaluation of disease;
- Alcohol and drug dependence or is being treated for a hormone drugs patients;
- Craniocerebral injury;
- Seizure or a family history of epilepsy;
- Pregnancy and lactation women;
See the full eligibility criteria
- Sign a written informed consent to participate in the trial and receive treatment;
- Major depressive disorder diagnosis;
- Hamilton depression scale (HAMD - 24) 24 total score 20 points or more;
- First episode or recurrence of depression patients, not taking psychiatric drugs;
- The han nationality, right-handed;
- Junior high school or above;
- Other organic mental disorders and mental retardation and other severe mental disorders;
- Infection, trauma, and autoimmune diseases or other possible interference test evaluation of disease;
- Alcohol and drug dependence or is being treated for a hormone drugs patients;
- Craniocerebral injury;
- Seizure or a family history of epilepsy;
- Pregnancy and lactation women;
- All landowners had a metal and MRI contraindications or MRI examination revealed abnormal brain structure.
The study team makes the final eligibility decision.
Where it's taking place
- Hangzhou, Zhejiang, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hangzhou, Zhejiang, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.