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Official title Air Pollution and Cardiovascular Disease in Qatar: an Interventional Study to Reduce Blood Pressure
ClinicalTrials.gov ID: NCT05903950
What this study is testing
- What it's testing
- The main objective is to determine if in-home portable air cleaners provide persistent reductions in PM2.5 exposures and improvements in systolic blood pressure and biochemical parameters over 4-weeks in patients with metabolic syndrome residing in Qatar.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Non-smokers (100% abstinence from use of any smoking or vaping product during the prior year)
- Age ≥18 and less than 60 years old
- Living in a single residence (home, apartment) located anywhere in Qatar
- Mild systolic hypertension: screening visit systolic BP 130 to 159 mm Hg (off treatment or taking ≤ 2 BP medications that have been stable without...
- Waist circumference ≥102 cm if male and ≥88 cm if female
You likely can't join if
- Pregnancy (self-reported)
- Screening visit urine positive for cotinine (NicAlert \>100 ng/mL)
- Living with an active smoker who smokes indoors (by self-report)
- High risk conditions that prohibit allowing home BP to be \>130/80 mm Hg during the10-week trial including any cardiovascular disease (coronary...
- A medical condition placing the participant at risk from participation (per investigators)
- Expected overnight travel outside their residence during the study
See the full eligibility criteria
- Non-smokers (100% abstinence from use of any smoking or vaping product during the prior year)
- Age ≥18 and less than 60 years old
- Living in a single residence (home, apartment) located anywhere in Qatar
- Mild systolic hypertension: screening visit systolic BP 130 to 159 mm Hg (off treatment or taking ≤ 2 BP medications that have been stable without changes during prior 4 weeks) plus ≥ 2 more additional criteria for the...
- Waist circumference ≥102 cm if male and ≥88 cm if female
- Fasting triglycerides ≥150 mg/dL (or taking a triglyceride-lowering medication)
- HDL-C ≤ 40 mg/dL if male and ≤ 50 mg/dL if female (or taking an HDL-raising medication),
- Fasting glucose ≥100 mg/dL
- Pregnancy (self-reported)
- Screening visit urine positive for cotinine (NicAlert \>100 ng/mL)
- Living with an active smoker who smokes indoors (by self-report)
- High risk conditions that prohibit allowing home BP to be \>130/80 mm Hg during the10-week trial including any cardiovascular disease (coronary artery disease, prior stroke, heart failure, peripheral arterial disease...
- A medical condition placing the participant at risk from participation (per investigators)
- Expected overnight travel outside their residence during the study
- HEPA filter within the air conditioners of the residence (self-reported) or individual use of HEPA filter
- Unable to comprehend/sign an informed consent
- Lung disease requiring oxygen
- Cancer receiving treatment
- Screening visit: BP ≥160/100 mm Hg or fasting blood glucose ≥126 mg/dL and confirmed diabetes with follow-up HbA1c ≥6.5%. If glucose is elevated ≥126 mg/dL but HbA1c\<6.5%, they could still participate.
- Medication changes in past 4 weeks. If participants are on medications for high BP or hyperlipidemia, they will need to have had stable therapy during prior 10 weeks with no planned changes during the study
- Left upper arm circumference \>17 inches as this will make BP levels inaccurate with the home monitor used
- Acute illness or infectious symptoms within the prior 4 weeks.
The study team makes the final eligibility decision.
Where it's taking place
- Doha, Qatar
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Doha, Qatar. Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.