BridgeMD
New treatment option for Alcohol Use Disorder, Severe
Official title Impact of Omega 3 in Alcohol Use Disorder
ClinicalTrials.gov ID: NCT05899660
What this study is testing
- What it's testing
- The goal of this clinical trial is to investigate the biological pathways underlying the beneficial effect of omega-3 polyunsaturated fatty acids (n-3 PUFA) on mental health in patients with alcohol use disorder. The main questions this study aims to answer are: Can n-3 PUFA improve mood disorders (depression, anxiety), craving for alcohol, cognitive impairments and sociability disorders ?
- Time commitment: about 3 months
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Diagnosis of alcohol use disorder (≥ 4 DSM-5 criteria)
- Patient at the hospital for a 3 week alcohol withdrawal program
- Gender : male and female
- Age : between 18 and 70 years old
- Language : french
You likely can't join if
- Presence of another addiction, except for smoking and cannabis use
- Presence of a psychiatric comorbidity (axis 1 DSM-5)
- Current or recent use (\< 2 months) of antibiotics, probiotics, fibre supplements
- Current or recent (\< 2 months) use of omega-3 supplements
- Current or recent (\< 2 months) use of oral anti-coagulants drugs
- Current or recent (\< 2 months) double anti-platelet therapy
See the full eligibility criteria
- Diagnosis of alcohol use disorder (≥ 4 DSM-5 criteria)
- Patient at the hospital for a 3 week alcohol withdrawal program
- Gender : male and female
- Age : between 18 and 70 years old
- Language : french
- Alcohol consumption less than 48 jours before admission
- Presence of another addiction, except for smoking and cannabis use
- Presence of a psychiatric comorbidity (axis 1 DSM-5)
- Current or recent use (\< 2 months) of antibiotics, probiotics, fibre supplements
- Current or recent (\< 2 months) use of omega-3 supplements
- Current or recent (\< 2 months) use of oral anti-coagulants drugs
- Current or recent (\< 2 months) double anti-platelet therapy
- Coagulation disorders
- Current or recent (\< 1 month) use of non-steroidal anti-inflammatory drugs and glucocorticoids
- Morbid obesity : body mass index \> 35 kg.m-2
- Bariatric surgery
- Type I diabetes and type II diabetes not stabilised (i.e. glycated haemoglobin \> 7.2 and unstable drug treatments)
- Chronic inflammatory diseases
- Cancer (less than 5 years before admission)
- Presence of cirrhosis (Fibroscan® = F4 and echodoppler performed as part of clinical routine on patient admission)
- Known allergy to fish and seafood
- Any other comorbidity that would be a contraindication to the study in the judgement of the principal investigator
The study team makes the final eligibility decision.
Where it's taking place
- Brussels, Belgium
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 3 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Brussels, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.