BridgeMD
New treatment option for Cirrhosis, Liver
Official title Online Prehabilitation for Patients Awaiting Liver Transplantation
ClinicalTrials.gov ID: NCT05899231
What this study is testing
- What it's testing
- Physical frailty is common in patients awaiting liver transplantation and has been associated with poor health outcomes. There is promising data from small studies showing that behavioural, nutrition, exercise therapy (prehabilitation) improves physical function in patients while they are waiting for a liver transplant.
- Time commitment: about 4 years
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- ≥18 years old with cirrhosis (confirmed with transient elastography by FibroScan, histology, or imaging-based assessment with compatible clinical...
You likely can't join if
- Listed for living related donor transplantation with expected time on the wait list \ 26 (Justification: time to transplant is very short)
- Robust status on frailty testing (LFI 0-3.1) (Justification: unlikely to see benefit)
- Unable to provide informed consent
- Presence of a clinical condition that makes the intervention unsafe or infeasible (e.g. unable to follow instruction) or unsafe environment for...
- Life expectancy less than 6 months, compassionate care (clinician judgment) (Justification: unlikely to see benefit)
- Recent variceal bleed or history of varices not on adequate prophylaxis (Justification: acute exercise increases portal pressure
See the full eligibility criteria
- ≥18 years old with cirrhosis (confirmed with transient elastography by FibroScan, histology, or imaging-based assessment with compatible clinical picture), referred for transplant and are assessed to have a high...
- Listed for living related donor transplantation with expected time on the wait list \ 26 (Justification: time to transplant is very short)
- Robust status on frailty testing (LFI 0-3.1) (Justification: unlikely to see benefit)
- Unable to provide informed consent
- Presence of a clinical condition that makes the intervention unsafe or infeasible (e.g. unable to follow instruction) or unsafe environment for virtual participation
- Life expectancy less than 6 months, compassionate care (clinician judgment) (Justification: unlikely to see benefit)
- Recent variceal bleed or history of varices not on adequate prophylaxis (Justification: acute exercise increases portal pressure
- Transplant indication is cholangiocarcinoma.
The study team makes the final eligibility decision.
Where it's taking place
- Calgary, Alberta, Canada
- Edmonton, Alberta, Canada
- Vancouver, British Columbia, Canada
- London, Ontario, Canada
- Toronto, Ontario, Canada
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 4 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Calgary, Alberta, Canada; Edmonton, Alberta, Canada; Vancouver, British Columbia, Canada; London, Ontario, Canada; Toronto, Ontario, Canada; Montreal, Quebec, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.