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New treatment option for Parkinson Disease
Official title Exercise Neuroprotection in Parkinson's Disease
ClinicalTrials.gov ID: NCT05854524
What this study is testing
- What it's testing
- The purpose of this study is to explore the relationships of exercise on inflammation in the body of older adults and people with Parkinson's disease (PD). This is important research for older adults but is especially important for people with PD because neuroinflammation is the main pathological mechanism that is responsible for neuron cell death in this neurodegenerative disease.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 30 to 85. Healthy volunteers may be eligible.
You may be able to join if
- for PwP:
- 30-85 years old
- Neurologist-diagnosed PD
- Able to participate in 30 minutes of continuous moderate aerobic exercise with 2-3 short breaks per self-report. for controls:
- 30-85 years old
You likely can't join if
- for both PD group and controls:
- Diagnoses, identified by self-report, that would preclude exercise participation (e.g., heart arrhythmias, uncontrolled blood pressure...
- Those not deemed ready for exercise participation. Participants will be screened for exercise participation using the Physical Activities Readiness...
- Those with dementia will be excluded because there are self-report questionnaires in this study. This will be identified using the Montreal Cognitive...
See the full eligibility criteria
- for PwP:
- 30-85 years old
- Neurologist-diagnosed PD
- Able to participate in 30 minutes of continuous moderate aerobic exercise with 2-3 short breaks per self-report. for controls:
- 30-85 years old
- No major medical diagnoses
- Able to participate in 30 minutes of continuous moderate aerobic exercise with 2-3 short breaks per self-report.
- for both PD group and controls:
- Diagnoses, identified by self-report, that would preclude exercise participation (e.g., heart arrhythmias, uncontrolled blood pressure, exercise-induced asthma).
- Those not deemed ready for exercise participation. Participants will be screened for exercise participation using the Physical Activities Readiness Questionnaire + which is used as a screening tool for all ages to...
- Those with dementia will be excluded because there are self-report questionnaires in this study. This will be identified using the Montreal Cognitive Assessment and a score at or below a 21. Participants with mild...
The study team makes the final eligibility decision.
Where it's taking place
- Las Vegas, Nevada, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 30 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Las Vegas, Nevada, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.