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Compares treatment options for Diminished Ovarian Reserve
Official title DPOS Versus GnRH Antagonist Protocol for Oocyte Accumulation in Low Ovarian Reserve Patients: An RCT
ClinicalTrials.gov ID: NCT05847283
What this study is testing
- What it's testing
- One of the barriers in patients with diminished ovarian reserve (DOR) is the significantly reduced number of oocytes resulting in fewer oocytes collected and embryos formed. Many ovarian stimulation strategies have been proposed to improve oocyte or embryo quantity which is oocyte accumulation could be a potential option with a comparable success rate and reasonable cost.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 37, women only. Healthy volunteers may be eligible.
You may be able to join if
- Woman aged between 18 and 37 years
- AFC ≤ 5 and/or AMH ≤ 1.2 ng/ml
- Agree to perform freeze-all strategy and single frozen blastocyst embryo transfer
You likely can't join if
- Oocyte recipient
- Indication of preimplantation genetic testing
- Known allergic reactions to medications in the Study (progesterone products, GnRH antagonist….)
- Basal FSH above 15mIU/mL.
- Have contraindications of ART treatment (e.g. critical or acute diseases)
- Retrieved sperm
See the full eligibility criteria
- Woman aged between 18 and 37 years
- AFC ≤ 5 and/or AMH ≤ 1.2 ng/ml
- Agree to perform freeze-all strategy and single frozen blastocyst embryo transfer
- Oocyte recipient
- Indication of preimplantation genetic testing
- Known allergic reactions to medications in the Study (progesterone products, GnRH antagonist….)
- Basal FSH above 15mIU/mL.
- Have contraindications of ART treatment (e.g. critical or acute diseases)
- Retrieved sperm
- Repeated Implantation failure ( ≥ 3 failed embryo transfers with good-quality embryos)
- Inability to comply with the study procedures.
- Patients with a history of thyroid cancer who are on hormone replacement therapy or those diagnosed with thyroid diseases at the time of eligibility assessment
The study team makes the final eligibility decision.
Where it's taking place
- Hanoi, Hanoi, Vietnam
- Ho Chi Minh City, Ho Chi Minh, Vietnam
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 37 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hanoi, Hanoi, Vietnam; Ho Chi Minh City, Ho Chi Minh, Vietnam. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.