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New treatment option for NAFLD
Official title Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals
ClinicalTrials.gov ID: NCT05842850
What this study is testing
- What it's testing
- The investigators will conduct a proof-of-principle 4-weeks low-calorie diet (LCD) intervention study in low birth weight (LBW) subjects and normal birth weight (NBW) controls with documented (MR scan) liver fat content equal to or above 5%. The investigators will provide extended in-depth mechanistic insight into the role of impaired subcutaneous adipose tissue (SAT) expandability in ectopic fat deposition before and after LCD.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 to 40
You may be able to join if
- people with NAFLD (liver fat content ≥5% liver fat content verified on MRS in the screening NAFLD study)
You likely can't join if
- BMI\ 30 kg/m2
- Family history of diabetes (siblings, parent, and grandparents)
- Disease/medication known to affect primary outcome
- Self-reported high physical activity level
- Alcohol intake above general recommendations.
- Metabolic/liver disease
See the full eligibility criteria
- people with NAFLD (liver fat content ≥5% liver fat content verified on MRS in the screening NAFLD study)
- BMI\ 30 kg/m2
- Family history of diabetes (siblings, parent, and grandparents)
- Disease/medication known to affect primary outcome
- Self-reported high physical activity level
- Alcohol intake above general recommendations.
- Metabolic/liver disease
- Weight gain/loss of \>3 kg within the past 6 months
The study team makes the final eligibility decision.
Where it's taking place
- Aarhus, Denmark
- Herlev, Denmark
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years to 40 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Aarhus, Denmark; Herlev, Denmark. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.