BridgeMD
New treatment option for Hypotension
Official title Treatment of Orthostatic Hypotension in SCI
ClinicalTrials.gov ID: NCT05839652
What this study is testing
What is Midodrine Hydrochloride?
Midodrine Hydrochloride is an investigational medicine, being studied as a potential treatment for hypotension.
Also referred to as Droxidopa.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- traumatic spinal cord injury
- at least 12 months post injury
- injury level of C1-T6
- AIS A, B or C
- non-ambulatory
You likely can't join if
- Active psychiatric disorder
- Stroke or cerebrovascular disease
- Alzheimer's Disease or dementia
- Unmanaged cardiac arrhythmias
- Concurrent systemic, hepatic, or renal disease
- Suspected or diagnosed malignancy
See the full eligibility criteria
- traumatic spinal cord injury
- at least 12 months post injury
- injury level of C1-T6
- AIS A, B or C
- non-ambulatory
- non-ventilator
- Active psychiatric disorder
- Stroke or cerebrovascular disease
- Alzheimer's Disease or dementia
- Unmanaged cardiac arrhythmias
- Concurrent systemic, hepatic, or renal disease
- Suspected or diagnosed malignancy
- Neurological disease other than SCI
- Self-reported history of three or more symptomatic episodes of AD per day
The study team makes the final eligibility decision.
Where it's taking place
- West Orange, New Jersey, United States
- The Bronx, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include West Orange, New Jersey, United States; The Bronx, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.