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Compares treatment options for Chest Trauma
Official title HFNC Compared With Facial Mask in Patients With Chest Trauma Patients
ClinicalTrials.gov ID: NCT05828030
What this study is testing
- What it's testing
- Guidelines for noninvasive ventilation (NIV) recommend continuous positive airway pressure in patients with thoracic trauma who remain hypoxic . However, no any suggestion was applied for high flow nasal cannula (HFNC).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 99
You may be able to join if
- Patients who have the following condition within 72 hours of chest trauma despite receiving standard nasal cannula oxygen therapy [≥10 L/min], are...
- severe hypoxemic respiratory failure [Arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen fraction(FiO2) \<300 mmHg]
- with a respiratory rate \>25 breaths/minute and difficulty breathing, or respiratory distress
- PaCO2 of 45 mmHg or higher (if the patient requires emergency surgery with endotracheal intubation and mechanical ventilation, the time of inclusion...
You likely can't join if
- Patients with a Glasgow Coma Scale less than 8 or severe brain injury.
- Patients with any contraindications to non-invasive ventilation, including acute gastrointestinal bleeding, upper airway obstruction, or hemodynamic...
- Facial trauma involving skull base fractures, facial bone fractures, or orbital floor fractures.
- Severe injuries involving the nasal sinuses.
- Patients with cervical spine injuries.
- Patients with increased intracranial pressure.
See the full eligibility criteria
- Patients who have the following condition within 72 hours of chest trauma despite receiving standard nasal cannula oxygen therapy [≥10 L/min], are eligible for inclusion.
- severe hypoxemic respiratory failure [Arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen fraction(FiO2) \<300 mmHg]
- with a respiratory rate \>25 breaths/minute and difficulty breathing, or respiratory distress
- PaCO2 of 45 mmHg or higher (if the patient requires emergency surgery with endotracheal intubation and mechanical ventilation, the time of inclusion will be the start of the post-extubation period. (Note: For patients...
- Patients with a Glasgow Coma Scale less than 8 or severe brain injury.
- Patients with any contraindications to non-invasive ventilation, including acute gastrointestinal bleeding, upper airway obstruction, or hemodynamic instability.
- Facial trauma involving skull base fractures, facial bone fractures, or orbital floor fractures.
- Severe injuries involving the nasal sinuses.
- Patients with cervical spine injuries.
- Patients with increased intracranial pressure.
- Patients with facial, nasal, or airway structural abnormalities or surgery that prevents the use of appropriate nasal cannula.
- Patients after upper airway surgery.
- Patients who are unable to clearly express their willingness to sign informed consent.
The study team makes the final eligibility decision.
Where it's taking place
- Taipei, Taipei, Taiwan
- Taipei, Taiwan, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 99 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taipei, Taipei, Taiwan; Taipei, Taiwan, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.