BridgeMD
Tests treatment safety and results for X-linked Retinoschisis
Official title Safety and Efficacy Study of LX103 Treatment of X-Linked Retinoschisis (XLRS)
ClinicalTrials.gov ID: NCT05814952
What this study is testing
What is LX103 Injection?
LX103 Injection is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for x-linked retinoschisis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this study is to evaluate the safety and efficacy of LX103 treatment of X-linked retinoschisis. This study will enroll subjects aged ≥ 6 years old to receive a single unilateral intravitreal (IVT) injection of LX103 to evaluate its safety and efficacy.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 6 and older, men only
You may be able to join if
- Willing to sign the informed consent, and willing to attend follow-up visits.
- Male individual at least 6 years of age with a diagnosis of XLRS and documented mutations in the RS1 gene.
- The study eye must have a best-corrected E-ETDRS visual acuity letter score of less than or equal to 63.
You likely can't join if
- Any eye with disease that would interfere with the fundus examinations.
- The study eye is receiving topical carbonic anhydrase inhibitor, or has received topical carbonic anhydrase inhibitors in the past three months.
- The study eye has undergone intraocular surgery within six months prior to enrollment.
- Participant has uncontrolled hypertension or diabetes.
The study team makes the final eligibility decision.
Where it's taking place
- Shanghai, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 6 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shanghai, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.