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New treatment option for Respiratory Tract Infections
Official title Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
ClinicalTrials.gov ID: NCT05758532
What this study is testing
What is Measles-Mumps-Rubella vaccine (MMR)?
Measles-Mumps-Rubella vaccine (MMR) is an investigational medicine, given as an injection into a muscle, being studied as a potential treatment for respiratory tract infections.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to evaluate the off-target/non-specific effects of the measles-mumps-rubella (MMR) vaccine in children.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 6 to 6. Healthy volunteers may be eligible.
You may be able to join if
- Informed Consent as documented by signature
- 6-month-old children
- In overall good health, without any clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular...
- Fully immunised for age according to the Swiss vaccination schedule
- with at least 2 doses of DTP-containing vaccine
You likely can't join if
- Contra-indications to MMR, including
- immunosuppression (i.e. proven, suspected, or planned)
- allergy to a component of the vaccine
- receipt of a live-attenuated vaccine in the four weeks prior to inclusion
- Vaccine refusal
- Indication for an early MMR vaccination, including
See the full eligibility criteria
- Informed Consent as documented by signature
- 6-month-old children
- In overall good health, without any clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular disease, etc.) and no clinically significant abnormal finding on history...
- Fully immunised for age according to the Swiss vaccination schedule
- with at least 2 doses of DTP-containing vaccine
- the last dose of vaccine received at least 2 weeks prior to enrolment
- Contra-indications to MMR, including
- immunosuppression (i.e. proven, suspected, or planned)
- allergy to a component of the vaccine
- receipt of a live-attenuated vaccine in the four weeks prior to inclusion
- Vaccine refusal
- Indication for an early MMR vaccination, including
- Measles outbreak
- Planned immunosuppression (indication to an accelerated schedule to be completed before starting an immunosuppressive treatment)
- Travel to a region with a high risk of measles outbreak
- Indication for vaccination with MMR-varicella (MMRV) instead of MMR, including
- severe eczema
- parental will
- Parental inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, known/suspected non-compliance, substance abuse, etc.
- Plan to move out of the country or have prolong absence during the trial
- Other sibling included in the trial (in the case of multiple pregnancy, only one child can be assigned by chance)
- Any temporary contra-indication to MMR, including child being sick (active significant illness, inclusion can be delayed a few days until the illness resolves)
The study team makes the final eligibility decision.
Where it's taking place
- Geneva, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 6 months to 6 months. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Geneva, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.