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Compares treatment options for Acute Hypoxemia
Official title Building Respiratory Support in East Africa Through High Flow Versus Standard Flow Oxygen Evaluation
ClinicalTrials.gov ID: NCT05754034
What this study is testing
- What it's testing
- Acute hypoxemia is common and deadly in resource variable settings. While studies in high income countries (HICs) have indicated a possible benefit to high flow oxygen as compared with standard flow oxygen, rigorous studies in low or lower middle income countries (LMICs) have not been performed.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- age\>=18 years AND
- admitted to a study site hospital within the 24 hours prior to screening AND
- SpO2\<90% at time of first assessment OR
- receiving oxygen at time of first assessment
You likely can't join if
- imminent death (high clinical suspicion of death within 24 hours of admission)
- patient or caregiver refusal of study participation
- history of chronic respiratory failure (SpO2\<90% or oxygen dependence for at least three months)
- anatomical factors precluding the use of nasal cannula
- intubation or non-invasive ventilation by the clinical team prior to screening for the trial
- known hypoxemia at transferring facility for \>48 hours
See the full eligibility criteria
- age\>=18 years AND
- admitted to a study site hospital within the 24 hours prior to screening AND
- SpO2\<90% at time of first assessment OR
- receiving oxygen at time of first assessment
- imminent death (high clinical suspicion of death within 24 hours of admission)
- patient or caregiver refusal of study participation
- history of chronic respiratory failure (SpO2\<90% or oxygen dependence for at least three months)
- anatomical factors precluding the use of nasal cannula
- intubation or non-invasive ventilation by the clinical team prior to screening for the trial
- known hypoxemia at transferring facility for \>48 hours
- lack of availability of either SFO or HFO devices or supplies at the time of randomization.
The study team makes the final eligibility decision.
Where it's taking place
- Kijabe, Kenya
- Nakuru, Kenya
- Blantyre, Malawi
- Huye, Rwanda
- Kigali, Rwanda
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kijabe, Kenya; Nakuru, Kenya; Blantyre, Malawi; Huye, Rwanda; Kigali, Rwanda. Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.