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New treatment option for Egg Allergy
Official title Oral Immunotherapy for Egg Allergy in Children Aged 6 to 16
ClinicalTrials.gov ID: NCT05740163
What this study is testing
- What it's testing
- The aim of the study is to determine the efficacy of a 12-month egg oral immunotherapy (OIT) protocol with a cooked whole egg product including yolk and egg white. Study hypothesis: With this method the risk for severe allergic reaction to egg protein is reduced and the diet can partly or completely be normalized.
- Time commitment: about 12 months
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 6 to 16
You may be able to join if
- Age 6 to 16 years
- Elevated spesific serum IgE to egg (\> 5 kU/l) and/or positive skin prick to egg allergen
- Positive oral food challenge for egg or anaphylaxis reaction to egg within the 6 months
- Diet free from egg in any form
You likely can't join if
- Age less than 6 years or more than 16 years
- Poor asthma control or uncontrolled asthma
- Severe/significant cardiovascular disease
- Autoimmune disease
- Malignancy
- Medication: beta bloker, angiotensin-converting-enzyme inhibitors (ACE inhibitors), Monoamine oxidase inhibitors (MAOIs)
See the full eligibility criteria
- Age 6 to 16 years
- Elevated spesific serum IgE to egg (\> 5 kU/l) and/or positive skin prick to egg allergen
- Positive oral food challenge for egg or anaphylaxis reaction to egg within the 6 months
- Diet free from egg in any form
- Age less than 6 years or more than 16 years
- Poor asthma control or uncontrolled asthma
- Severe/significant cardiovascular disease
- Autoimmune disease
- Malignancy
- Medication: beta bloker, angiotensin-converting-enzyme inhibitors (ACE inhibitors), Monoamine oxidase inhibitors (MAOIs)
- Poor compliance
- Fear of immunotherapy
- Desensitization to alfa-gal-protein (mammalian meat allergy)
The study team makes the final eligibility decision.
Where it's taking place
- Oulu, Finland
- Tampere, Finland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 12 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 6 years to 16 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Oulu, Finland; Tampere, Finland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.