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New treatment option for Alcohol Use Disorder
Official title Cerebellar Involvement in Alcohol Use Disorder (AUD)
ClinicalTrials.gov ID: NCT05732207
What this study is testing
- What it's testing
- The goal of this observational and interventional study is to better understand the involvement of the cerebellum in the brain reward system in persons with alcohol use disorder (AUD). The main questions it aims to answer are: 1.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 25 to 55. Healthy volunteers may be eligible.
You may be able to join if
- completed at least 8 years of education
You likely can't join if
- Estimated Intelligence Quotient (IQ) \< 90
- less than 5th grade reading level
- Left handed
- Non-fluent in English
- current drug use disorder other than alcohol (except nicotine and caffeine) and or recent drug use in the last 90 days
- Positive breath alcohol level at time of MRI scan or discrepancies between alcohol biomarker and self-report that cannot be resolved
See the full eligibility criteria
- completed at least 8 years of education
- Estimated Intelligence Quotient (IQ) \< 90
- less than 5th grade reading level
- Left handed
- Non-fluent in English
- current drug use disorder other than alcohol (except nicotine and caffeine) and or recent drug use in the last 90 days
- Positive breath alcohol level at time of MRI scan or discrepancies between alcohol biomarker and self-report that cannot be resolved
- Exhibiting symptoms of alcohol withdrawal on visit 1 assessment
- Significant current psychiatric distress and or treatment
- History of any central nervous system disorder, presence of a seizure disorder, or use of anticonvulsant medication in the past 3 months
- any serious medical condition detected on assessment or by medical record review; or have liver function tests more than three times normal at screening
- History of metal implantation that would preclude MRI scanning; or other implants, pumps, pacemakers that would be contraindications for MRI scanning
- Abnormal MRI scan or history of significant closed head trauma
- Evidence of dementia
- For women, pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Baltimore, Maryland, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 25 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Baltimore, Maryland, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.