BridgeMD
New treatment option for Stroke, Ischemic
Official title Evaluation and Prediction of the Effect of EECP on HR-NICE Patients
ClinicalTrials.gov ID: NCT05718622
What this study is testing
- What it's testing
- Stroke is one of the most threatening causes of mortality and disability worldwide. High risk non-disabling ischemic cerebrovascular events (HR-NICE), defined by mild stroke complicating with greater than 50% atherosclerotic stenosis in intracranial or extracranial arteries, is more likely to develop severe stroke in future.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80. Healthy volunteers may be eligible.
You may be able to join if
- In accordance with the diagnostic criteria of Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018
- Patients who have had a clinically significant ischemic stroke for the first time and are currently stable
- Unilateral internal carotid artery or middle cerebral artery was confirmed for the first time as moderate to severe stenosis (≥50%) or occlusion on...
- Did not receive surgical treatment such as balloon dilation
- National Institute of Health stroke scale (NIHSS) score ≤3
You likely can't join if
- Progressive stroke
- Diseases with severe damage to other organs
- Moderate to severe aortic insufficiency
- Dissection aneurysm, aortic aneurysm, cerebral aneurysm
- Significant pulmonary hypertension
- Various bleeding disorders, bleeding tendencies, or use of anticoagulants, Prothrombin international normalized ratio （INR） \>2.0
See the full eligibility criteria
- In accordance with the diagnostic criteria of Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018
- Patients who have had a clinically significant ischemic stroke for the first time and are currently stable
- Unilateral internal carotid artery or middle cerebral artery was confirmed for the first time as moderate to severe stenosis (≥50%) or occlusion on digital subtraction angiography examination （DSA）.
- Did not receive surgical treatment such as balloon dilation
- National Institute of Health stroke scale (NIHSS) score ≤3
- The clinical data is completed and be able to consistently complete the study
- Age 18-80, education level≥ 6 years and agree to sign informed consent
- Progressive stroke
- Diseases with severe damage to other organs
- Moderate to severe aortic insufficiency
- Dissection aneurysm, aortic aneurysm, cerebral aneurysm
- Significant pulmonary hypertension
- Various bleeding disorders, bleeding tendencies, or use of anticoagulants, Prothrombin international normalized ratio （INR） \>2.0
- Active phlebitis, venous embolism, venous thrombosis of lower extremity
- The presence of infection in the body
- Valvular disease, congenital heart disease, cardiomyopathy
- Uncontrolled hypertension (\>170/110mmHg)
- Uncontrolled arrhythmia
- Left heart failure
- Pregnancy
- Patients with cardiac pacemakers
- Patients with arterial clamp after craniocerebral operation
- Patients with metal implants, such as metal joints, shrapnel and orbital foreign bodies
- History of moderate to severe cognitive impairment or psychiatric disorders
- History of malignancy
- moyamoya patients
- Lower extremity arterial thrombosis
The study team makes the final eligibility decision.
Where it's taking place
- Xi'an, Shaanxi, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Xi'an, Shaanxi, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.