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New treatment option for Low Back Pain, Recurrent
Official title Exercise Therapy for Recurrent Low Back Pain: Unraveling the Puzzle of Peripheral Muscle and Central Brain Changes (B670201420984)
ClinicalTrials.gov ID: NCT05706103
What this study is testing
- What it's testing
- Exercise therapy has been shown to be effective in decreasing pain and improving function for patients with recurrent low back pain (LBP). Research on the mechanisms that trigger and/or underlie the effects of exercise therapy on LBP problems is of critical importance for the prevention of recurring or persistence of this costly and common condition.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45
You may be able to join if
- History of non-specific recurrent LBP with the first onset being at least 6 months ago
- At least 2 episodes of LBP/year, with an 'episode' implying pain lasting a minimum of 24 hours which is preceded and followed by at least 1 month...
- Minimum LBP intensity during episodes should be ≥2/10 on a numeric rating scale (NRS) from 0 to 10
- During remission the NRS intensity for LBP should be 0.
- LBP should be of that severity that it limits activities of daily living
You likely can't join if
- Chronic LBP (i.e. duration remission \<1 month)
- Subacute LBP (i.e. first onset between 3 and 6 months ago)
- Acute (i.e. first onset \<3 months ago) LBP
- Specific LBP (i.e. LBP proportionate to an identifiable pathology, e.g. lumbar radiculopathy)
- Patients with neuropathic pain
- Patients with chronic widespread pain as defined by the criteria of the 1990 ACR (i.e. fibromyalgia)
See the full eligibility criteria
- History of non-specific recurrent LBP with the first onset being at least 6 months ago
- At least 2 episodes of LBP/year, with an 'episode' implying pain lasting a minimum of 24 hours which is preceded and followed by at least 1 month without LBP
- Minimum LBP intensity during episodes should be ≥2/10 on a numeric rating scale (NRS) from 0 to 10
- During remission the NRS intensity for LBP should be 0.
- LBP should be of that severity that it limits activities of daily living
- LBP should be of that severity that a (para)medic has been consulted at least once regarding the complaints
- Flexion pattern of LBP
- Chronic LBP (i.e. duration remission \<1 month)
- Subacute LBP (i.e. first onset between 3 and 6 months ago)
- Acute (i.e. first onset \<3 months ago) LBP
- Specific LBP (i.e. LBP proportionate to an identifiable pathology, e.g. lumbar radiculopathy)
- Patients with neuropathic pain
- Patients with chronic widespread pain as defined by the criteria of the 1990 ACR (i.e. fibromyalgia)
- A lifetime history of spinal traumata (e.g. whiplash), surgery (e.g. laminectomy) or deformations (e.g. scoliosis)
- A lifetime history of respiratory, metabolic, neurologic, cardiovascular, inflammatory, orthopedic or rheumatologic diseases
- Concomitant therapies (i.e. rehabilitation, alternative medicine or therapies)
- Contra-indications for MRI (e.g. suffering from claustrophobia, the presence of metallic foreign material in the body, BMI \>30kg/m²)
- Professional athletes
- Pregnant women
- Breastfeeding women
- Women given birth in the last year before enrolment
The study team makes the final eligibility decision.
Where it's taking place
- Ghent, Oost-Vlaanderen, Belgium
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 45 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ghent, Oost-Vlaanderen, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.