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New treatment option for Cardiogenic Shock
Official title Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO
ClinicalTrials.gov ID: NCT05699005
What this study is testing
What is Packed Red Blood Cells (PRBCs)?
Packed Red Blood Cells (PRBCs) is an investigational medicine, being studied as a potential treatment for cardiogenic shock.
Also referred to as ScVO2 assesment to guide transfusion.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This multicenter randomized controlled trial compare two transfusion strategies of red blood cells transfusion in patients supported by veno-arterial extracorporeal membrane oxygenation for refractory cardiogenic shock. An individualized transfusion strategy based on ScVO2 level, is compared to a conventionnal strategy based on predefined hemoglobin threshold.
- Phase 1: an early, usually small safety study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age of 18 and older,
- supported by peripheral VA-ECMO
- for cardiogenic shock
- Life expentency \>90 days
- Central venous line available ScVO2 measurement
You likely can't join if
- Pregnancy,
- Lack of health insurance,
- Opposition to blood transfusion,
- Known congenital hemoglobin disease or disorder,
- Metabolic alcaloosis with pH\>7.8,
- eCPR,
See the full eligibility criteria
- Age of 18 and older,
- supported by peripheral VA-ECMO
- for cardiogenic shock
- Life expentency \>90 days
- Central venous line available ScVO2 measurement
- Pregnancy,
- Lack of health insurance,
- Opposition to blood transfusion,
- Known congenital hemoglobin disease or disorder,
- Metabolic alcaloosis with pH\>7.8,
- eCPR,
- Legally incapacitated adults
The study team makes the final eligibility decision.
Where it's taking place
- Lille, NORD, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lille, NORD, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.