BridgeMD
New treatment option for GERD
Official title Mechanisms Preventing Pharyngeal Reflux
ClinicalTrials.gov ID: NCT05696184
What this study is testing
- What it's testing
- The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85. Healthy volunteers may be eligible.
You may be able to join if
- Age 18 to 85
- GERD patients with complaints of regurgitation and supra-esophageal symptoms will be included and recruited from our GI \& Otolaryngology clinics
- GERD patients without complaint of supra-esophageal symptoms and regurgitation will be included and recruited from our GI \& Otolaryngology clinics
- Asthma patients with and without supra-esophageal symptoms will be included and recruited from clinics affiliated with Medical College of Wisconsin...
- Patient definition will be based on position statement and technical reviews of the American Gastroenterological Association and Montreal definition...
You likely can't join if
- Age \ 85
- Active alcohol or drug abuse
- History of ear, nose, throat and pulmonary diseases suspected of being GERD induced
- History of head and neck malignancy and chemo-radiation therapy to the head and neck
- Unable to give consent
- Pregnant women (see justification in the Women and Minority Inclusion in Clinical Research section)
See the full eligibility criteria
- Age 18 to 85
- GERD patients with complaints of regurgitation and supra-esophageal symptoms will be included and recruited from our GI \& Otolaryngology clinics
- GERD patients without complaint of supra-esophageal symptoms and regurgitation will be included and recruited from our GI \& Otolaryngology clinics
- Asthma patients with and without supra-esophageal symptoms will be included and recruited from clinics affiliated with Medical College of Wisconsin. Asthma patients with the following classifications of asthma severity...
- Patient definition will be based on position statement and technical reviews of the American Gastroenterological Association and Montreal definition and classification of gastroesophageal and reflux disease (Am J...
- SERD is defined as patients on long term acid suppressive therapy complaining of persistent regurgitation along with supra-esophageal manifestations such as burning throat, asthma, chronic cough, or hoarseness. Patients...
- Barrett's esophagus patients will be recruited based on histological diagnosis from previous endoscopic biopsy that will be found using the clinical database warehouse.
- Age \ 85
- Active alcohol or drug abuse
- History of ear, nose, throat and pulmonary diseases suspected of being GERD induced
- History of head and neck malignancy and chemo-radiation therapy to the head and neck
- Unable to give consent
- Pregnant women (see justification in the Women and Minority Inclusion in Clinical Research section)
- History of allergy to Lidocaine for nasal topical anesthesia
- Allergy to green food dye
- Asthma patients with an acute asthma exacerbation with symptoms including breathlessness, wheezing, and chest tightness
The study team makes the final eligibility decision.
Where it's taking place
- Milwaukee, Wisconsin, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Milwaukee, Wisconsin, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.