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Compares treatment options for Glaucoma
Official title Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting
ClinicalTrials.gov ID: NCT05694858
What this study is testing
What is Lignocaine-loaded maltose microneedle array patch?
Lignocaine-loaded maltose microneedle array patch is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for glaucoma.
Also referred to as Lignocaine-embedded microneedle array patch.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Microneedle (MN) is a mimic of a hypodermic needle, composed of hundreds of micron-sized, out-of-plane protrusions, typically arranged in arrays on a patch that can be applied onto the skin. MN can be fabricated from a variety of materials, preferably biocompatible polymers.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Patients aged 18 years old and above
- Patients requiring venepuncture for blood investigations before ophthalmological procedures
You likely can't join if
- Patient with a previous history of sensitization or allergy to lignocaine.
- Patient with a previous history of allergy to materials used in the study i.e., plaster, electrodes, maltose, Polyvinyl Alcohol (PVA), and...
- Patient exposed to analgesic usage within 24 hours prior to the procedure
- Generalized skin disorder/ rash
- Agitated/ fretful / uncooperative patient
- Uncommunicative/deaf/mute patients
See the full eligibility criteria
- Patients aged 18 years old and above
- Patients requiring venepuncture for blood investigations before ophthalmological procedures
- Patient with a previous history of sensitization or allergy to lignocaine.
- Patient with a previous history of allergy to materials used in the study i.e., plaster, electrodes, maltose, Polyvinyl Alcohol (PVA), and Polyethylene Terephthalate (PET)
- Patient exposed to analgesic usage within 24 hours prior to the procedure
- Generalized skin disorder/ rash
- Agitated/ fretful / uncooperative patient
- Uncommunicative/deaf/mute patients
- Patients on hypnotics, or chronic pain relief medications
- Patients with psychiatric conditions
- Patients with hepatic impairment
- Patients who are on CYP450 3A4, 3A5 or 1A2-inducing or inhibiting drugs (erythromycin, ciprofloxacin, amiodarone etc.) or pharmacotherapeutic agents that affect hepatic blood flow (metoprolol) since both may affect the...
- Failed first/single attempt at venepuncture after the application of the LEMAP or PET patch for control arm.
The study team makes the final eligibility decision.
Where it's taking place
- Kuala Lumpur, Kuala Lumpur, Malaysia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kuala Lumpur, Kuala Lumpur, Malaysia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.