BridgeMD
New treatment option for Autoinflammatory Disease
Official title Flemish Joint Effort for Biomarker PRofiling in Inflammatory Systemic Diseases
ClinicalTrials.gov ID: NCT05670301
What this study is testing
- What it's testing
- A multi-centre, prospective study to study cytokine profiles and other potential disease-specific biomarkers in patients with presumed or confirmed diseases of systemic inflammation The goal of this prospective, observational study is to describe the longitudinal evolution of blood cytokine profiles in patients with presumed or confirmed diseases of systemic inflammation The main questions it aims to answer are: What are the differences and similarities in blood cytokines between different patients and groups presenting symptoms of systemic inflammatory conditions? How is the cytokine profile of individual patients evolving over time and what is the effect of different therapeutics?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults. Healthy volunteers may be eligible.
You may be able to join if
- An individual who meets any of the following criteria can be eligible for participation in this study:
- Child or adult
- Written informed consent
- Suspected or confirmed disease with systemic inflammation (acute, chronic and/or recurrent), these include:
- Autoinflammatory diseases (AID), including among others: systemic onset juvenile idiopathic arthritis (sJIA), familial mediterranean fever (FMF)...
You likely can't join if
- An individual who meets any of the following criteria will be excluded from participation in this study:
- Confirmed localized infection and/or good response to first-line antibiotic treatment
- Confirmed malignancy Besides the above mentioned patients, volunteers that meet the requirements as a healthy individual are eligible for inclusion...
See the full eligibility criteria
- An individual who meets any of the following criteria can be eligible for participation in this study:
- Child or adult
- Written informed consent
- Suspected or confirmed disease with systemic inflammation (acute, chronic and/or recurrent), these include:
- Autoinflammatory diseases (AID), including among others: systemic onset juvenile idiopathic arthritis (sJIA), familial mediterranean fever (FMF), mevalonate kinase deficiency (Hyper IgD syndrome), TNF...
- Autoimmune diseases (AI), including among others: systemic lupus erythematosus (SLE), juvenile dermatomyositis (JDM), rheumatoid arthritis (RA),…
- Hyperinflammatory diseases, including among others: hemophagocytic lymphohistiocytosis (HLH), macrophage activation syndrome (MAS), infection-related cytokine storm (e.g. in the setting of COVID-19)
- Other unidentified or not yet identified systemic inflammatory conditions
- Blood sample for diagnostic purposes is planned and possibility to acquire additional blood volume
- An individual who meets any of the following criteria will be excluded from participation in this study:
- Confirmed localized infection and/or good response to first-line antibiotic treatment
- Confirmed malignancy Besides the above mentioned patients, volunteers that meet the requirements as a healthy individual are eligible for inclusion as controls.
The study team makes the final eligibility decision.
Where it's taking place
- Antwerp, Belgium
- Brussels, Belgium
- Ghent, Belgium
- Hasselt, Belgium
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Antwerp, Belgium; Brussels, Belgium; Ghent, Belgium; Hasselt, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.