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New treatment option for Psoriasis
Official title Dietary Approach to Mild-to-moderate Psoriasis
ClinicalTrials.gov ID: NCT05644782
What this study is testing
- What it's testing
- Psoriasis is a systemic chronic inflammatory immune-mediated disease whose etiopathogenetic mechanisms involve genetic predisposition, and immunological and environmental factors. Its prevalence is about 3% in adults, and it is characterized by well-demarcated, erythematous plaques, covered by silvery-white scales, in elbows, knees, trunk, and scalp.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- of psoriasis patients
- age \>18 and \<65 years;
- no systemic therapy for psoriasis for at least 3 months before inclusion in the study;
- negativity of anti-deamidated gliadin protein (anti-DGP) immunoglobulins (Ig) class A (IgA) and immunoglobulins (Ig)G, anti-tissue transglutaminase...
- absence of WA (negative prick-test and/or specific serum immunoglobulins (Ig)E assay for wheat, gluten, and gliadin).
You likely can't join if
- of psoriasis patients age \ 65 years;
- severe chronic plaque-type psoriasis (based on BSA);
- self-exclusion of gluten/wheat from the diet and refusal to reintroduce it, for diagnostic purposes, before entering the study;
- pregnancy;
- alcohol and/or drug abuse;
- Helicobacter pylori and other bacterial and/or parasitic infections;
See the full eligibility criteria
- of psoriasis patients
- age \>18 and \<65 years;
- no systemic therapy for psoriasis for at least 3 months before inclusion in the study;
- negativity of anti-deamidated gliadin protein (anti-DGP) immunoglobulins (Ig) class A (IgA) and immunoglobulins (Ig)G, anti-tissue transglutaminase (anti-tTG) class IgA and IgG, and Endomysium antibodies (EmA);
- absence of WA (negative prick-test and/or specific serum immunoglobulins (Ig)E assay for wheat, gluten, and gliadin).
- of psoriasis patients age \ 65 years;
- severe chronic plaque-type psoriasis (based on BSA);
- self-exclusion of gluten/wheat from the diet and refusal to reintroduce it, for diagnostic purposes, before entering the study;
- pregnancy;
- alcohol and/or drug abuse;
- Helicobacter pylori and other bacterial and/or parasitic infections;
- diagnosis of chronic inflammatory bowel disease and other organic pathology affecting the digestive system (e.g., severe liver disease), nervous system diseases, major psychiatric disorders, immunological deficits, and...
- diagnosis of cancer
- treatment with steroids and/or immunological therapies;
- patients undergoing chemotherapy and/or radiotherapy.
The study team makes the final eligibility decision.
Where it's taking place
- Palermo, Palermo, Italy
- Palermo, PA, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Palermo, Palermo, Italy; Palermo, PA, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.