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New treatment option for Acute Respiratory Distress Syndrome
Official title Inflammation During ECMO Therapy and ECMO Weaning
ClinicalTrials.gov ID: NCT05640635
What this study is testing
- What it's testing
- The goal of this interventional clinical trial is to compare patients who undergo ECMO therapy for treatment of acute respiratory distress syndrome (ARDS) and a randomized into one of two possible weaning strategy groups. Group 1: Weaning from ventilator occurs before ECMO weaning.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Acute respiratory distress syndrome (ARDS) according to the Berlin Definition (PaO2/FiO2 \< 100) and treatment with veno-venous ECMO (vvECMO)
- Hemodynamic stability
- Lung compliance did not change/improved during the last 24 hours
- Tidal volume did not change/improved during the last 24 hours with a PEEP of 10 cmH20 or above
- Consent of the patient or their legal representative
You likely can't join if
- Age \< 18 years
- Artificial ventilation for more than 7 days prior
- Patient, legal representative or doctors decided against an unrestricted intensive care treatment
- Positive pregnancy test at time of screening
- Cardiac failure requiring veno-arterial ECMO therapy
- Chronic respiratory insufficiency requiring long-term oxygen treatment
The study team makes the final eligibility decision.
Where it's taking place
- Tübingen, Baden-Wurttemberg, Germany
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tübingen, Baden-Wurttemberg, Germany. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.