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Tests treatment safety and results for Viral Lung Infection and Acute Respiratory Failure
Official title Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
ClinicalTrials.gov ID: NCT05624450
What this study is testing
What is Tozorakimab?
Tozorakimab is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for viral lung infection and acute respiratory failure.
Also referred to as MEDI3506.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to evaluate the effect of tozorakimab, as an add-on to SoC in patients with viral lung infection requiring supplemental oxygen, on the prevention of death or progression to IMV/ECMO.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult participants ≥ 18 years old at the time of signing the informed consent form.
- Patients hospitalised with viral lung infection.
- Hypoxaemia requiring treatment with supplemental O2. Hypoxaemia is defined as: SpO2 ≤ 90% OR SpO2 ≤ 92% AND one or both of the following...
You likely can't join if
- Known fungal or parasitic lung infection, aspiration lung infection, lung abscess, or evidence of septic shock. Bacterial co-infection is allowed...
- Hypoxaemia caused primarily by extrapulmonary insult or by lung injury of non-infective aetiology.
- Ongoing IMV/ECMO at randomisation.
The study team makes the final eligibility decision.
Where it's taking place
- Mobile, Alabama, United States
- Phoenix, Arizona, United States
- Tucson, Arizona, United States
- Chula Vista, California, United States
- Fresno, California, United States
- La Mesa, California, United States
- Los Angeles, California, United States
- Newport Beach, California, United States
- Torrance, California, United States
- Colorado Springs, Colorado, United States
- Denver, Colorado, United States
- Washington D.C., District of Columbia, United States
- Bradenton, Florida, United States
- Gainesville, Florida, United States
- Jacksonville, Florida, United States
- Lakeland, Florida, United States
- Miami, Florida, United States
- South Pasadena, Florida, United States
- St. Petersburg, Florida, United States
- Tampa, Florida, United States
+ 355 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Mobile, Alabama, United States; Phoenix, Arizona, United States; Tucson, Arizona, United States; Chula Vista, California, United States; Fresno, California, United States; La Mesa, California, United States and 369 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.