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Tests treatment safety and results for Cardiac Arrest
Official title Hydrogen's Feasibility and Safety as a Therapy in ECPR
ClinicalTrials.gov ID: NCT05574296
What this study is testing
What is Hydrogen?
Hydrogen is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for cardiac arrest.
Also referred to as H2 gas.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this project is to test the feasibility and safety of inhaled hydrogen gas (H2) administration as a rescue therapy during cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR, i.e. mechanical circulatory support).
- Phase 1: an early, usually small safety study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Patients admitted to a cardiac intensive care unit at a participating site with cardiac comorbidity, including congenital heart disease, myocarditis...
- Patients are anticipated to be between birth to 18 years of age, although occasionally a patient over the age of 18 may be enrolled.
- Patient experiencing a refractory cardiac arrest \>5 minutes and receiving ongoing CPR in the ICU, cardiac catheterization lab, or cardiac operating...
- The decision made by the clinical team to resuscitate from ongoing, refractory cardiac arrest using ECPR due to a lack of other available options.
You likely can't join if
- Meeting any of the following criterion renders the patient ineligible for the trial:
- Enrollment in the opt-out program.
- Patients known to be pregnant.
- Patients who are prisoners.
- Prior ECPR episode during admission (whether or not they were enrolled in the trial).
- Enrollment does not occur within 6 hours of the decision to resuscitate using ECPR. Note that ECMO cannulation without preceding CPR does not qualify...
The study team makes the final eligibility decision.
Where it's taking place
- Washington D.C., District of Columbia, United States
- Boston, Massachusetts, United States
- Kansas City, Missouri, United States
- Salt Lake City, Utah, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Washington D.C., District of Columbia, United States; Boston, Massachusetts, United States; Kansas City, Missouri, United States; Salt Lake City, Utah, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.