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New treatment option for Tourette Syndrome in Adolescence
Official title Neurofeedback From the Supplementary Motor Area for Tourette Syndrome
ClinicalTrials.gov ID: NCT05558566
What this study is testing
- What it's testing
- This is a clinical trial where adolescents aged 10-16 years old with Tourette Syndrome (or chronic tic disorder) are randomized to receive either real-time functional magnetic resonance imaging (fMRI) neurofeedback targeting the supplementary motor area (for the experimental intervention) or real-time fMRI neurofeedback (NF) from a control region (for the control intervention).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 10 to 16
You may be able to join if
- Boys and girls, 10 to 16 years of age
- A current diagnosis of Tourette Syndrome (TS) or chronic tic disorder (CTD), with active tics that can be executed without head movement, and a YGTSS...
- Currently stable medication treatment and no planned changes in medication for the duration of the study.
- Family residence within 2 hours of Yale Medical Center with ability and willingness to attend assessment and fMRI visits.
- Children and their parents are expected to be able to speak and understand spoken English in order to participate in a clinical assessment of TS and...
You likely can't join if
- Intelligence quotient below 80
- Current diagnosis of autism spectrum disorder, bipolar or psychotic disorder or current suicidality
- Significant medical condition such as heart disease, hypertension, liver or renal failure, pulmonary disease, seizure disorder
- Recently initiated psychotherapy. Participation in the study will not be allowed within 8 weeks of the initiation of psychotherapy. Ongoing...
- people may also be excluded after the first MR scan if we are unable to localize the two regions in their brain that are used as targets for the...
See the full eligibility criteria
- Boys and girls, 10 to 16 years of age
- A current diagnosis of Tourette Syndrome (TS) or chronic tic disorder (CTD), with active tics that can be executed without head movement, and a YGTSS score of at least 13 (for TS participants) or at least 12 (for CTD...
- Currently stable medication treatment and no planned changes in medication for the duration of the study.
- Family residence within 2 hours of Yale Medical Center with ability and willingness to attend assessment and fMRI visits.
- Children and their parents are expected to be able to speak and understand spoken English in order to participate in a clinical assessment of TS and related psychopathology.
- people will be free of: 1) metal medical implants or braces, 2) pregnancy, and will have 3) a body weight of less than 250 lbs. and 4) no claustrophobia.
- Intelligence quotient below 80
- Current diagnosis of autism spectrum disorder, bipolar or psychotic disorder or current suicidality
- Significant medical condition such as heart disease, hypertension, liver or renal failure, pulmonary disease, seizure disorder
- Recently initiated psychotherapy. Participation in the study will not be allowed within 8 weeks of the initiation of psychotherapy. Ongoing, concurrent psychotherapy (that was initiated at least 8 weeks previously) for...
- people may also be excluded after the first MR scan if we are unable to localize the two regions in their brain that are used as targets for the active and control neurofeedback conditions.
The study team makes the final eligibility decision.
Where it's taking place
- New Haven, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 10 years to 16 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New Haven, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.