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Official title Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain
ClinicalTrials.gov ID: NCT05555576
What this study is testing
- What it's testing
- Recent evidence has shown that vitamin C has some analgesic properties and can therefore reduce opioids used during healing. Vitamin C analgesic effect has been explored mostly during the short-term postoperative context or in disease specific chronic pain prevention but not after acute musculoskeletal injuries, which are often seen in the emergency department (ED).
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Aged 18 and over;
- Treated in ED for acute musculoskeletal pain present for less than 2 weeks;
- Discharged with an opioid prescription;
- Speaks French or English.
You likely can't join if
- Opioid use 1 month prior to the ED visit;
- Already taking vitamin C supplement;
- Active cancer;
- Treated for chronic pain;
- Treated for opioid use disorder;
- Unable to fill out diary or unavailable for follow-up;
See the full eligibility criteria
- Aged 18 and over;
- Treated in ED for acute musculoskeletal pain present for less than 2 weeks;
- Discharged with an opioid prescription;
- Speaks French or English.
- Opioid use 1 month prior to the ED visit;
- Already taking vitamin C supplement;
- Active cancer;
- Treated for chronic pain;
- Treated for opioid use disorder;
- Unable to fill out diary or unavailable for follow-up;
- Any allergy, intolerance or sensitivity to milk (lactose) or morphine
- Treated with cyclosporin or coumadin
- Pregnant or lactating (dosage \> 1,800 mg not recommended. For women of child-bearing age and sexually active in the past 3 months, a urine pregnancy test will be performed.)
The study team makes the final eligibility decision.
Where it's taking place
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Montreal, Quebec, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.