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New treatment option for Sarcopenia
Official title RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration
ClinicalTrials.gov ID: NCT05525039
What this study is testing
- What it's testing
- The investigators' pre-clinical study confirms the positive effects of combined treatment (VT + HMB) on reducing fat-to-lean tissue ratio, intramuscular fat infiltration and increasing muscle strength in sarcopenia animal model. The results showed that fat mass could be decreased by \~32%, while histology Oil Red O staining indicated a decrease of fat by almost 60%; in contrast, lean muscle mass increased by \~14%.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 and older
You may be able to join if
- people aged 60 years or above
- people failed in AWGS algorithm
- skeletal muscle mass by BIA (male at \<7.0 kg/m\^2, female at \<5.7 kg/m\^2), and
- handgrip strength (male at \<28 kg, female at \<18kg), and/or
- gait speed test (\>1m/s)
You likely can't join if
- people with pathological bone diseases
- people with chronic inflammatory condition (e.g. rheumatoid arthritis)
- people with neurological problems
- people receiving regular exercise
- Subjecs who are chair-/bed- bound
- people with malignancy
See the full eligibility criteria
- people aged 60 years or above
- people failed in AWGS algorithm
- skeletal muscle mass by BIA (male at \<7.0 kg/m\^2, female at \<5.7 kg/m\^2), and
- handgrip strength (male at \<28 kg, female at \<18kg), and/or
- gait speed test (\>1m/s)
- people with pathological bone diseases
- people with chronic inflammatory condition (e.g. rheumatoid arthritis)
- people with neurological problems
- people receiving regular exercise
- Subjecs who are chair-/bed- bound
- people with malignancy
- people with cardiovascular concern such as with pace-maker in-situ
- people with acute fractures or severe osteoarthritis
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.