BridgeMD
Compares treatment options for Gout
Official title Tight Control of Gouty Arthritis Compared to Usual Care
ClinicalTrials.gov ID: NCT05507723
What this study is testing
- What it's testing
- Gout is caused by a reaction to urate crystals that results in attacks of severe joint pain. Medicines that lower urate levels can prevent gout flares, however it takes time for this benefit to be felt, and paradoxically starting treatment with large doses of urate lowering treatment risks provoking attacks of gout.
- Time commitment: about 2 years
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Provision of informed consent.
- Age ≥18 years.
- Patient has sustained at least one flare of gout in the previous 12 months.
- Confirmed clinical diagnosis of gout as per ACR/EULAR criteria
- Serum urate \>0.36mm/L.
You likely can't join if
- Subject unable to provide consent
- Patient on maximum urate lowering therapy or where therapy cannot be escalated further due to intolerance/adverse reaction to either allopurinol or...
- End stage renal failure/transplant
- Current prescription of medication known to interact with xanthine oxidase inhibitors such as azathioprine or mercapto-purine.
See the full eligibility criteria
- Provision of informed consent.
- Age ≥18 years.
- Patient has sustained at least one flare of gout in the previous 12 months.
- Confirmed clinical diagnosis of gout as per ACR/EULAR criteria
- Serum urate \>0.36mm/L.
- Patient has a smart phone and is able to install GoutSMART application.
- Subject unable to provide consent
- Patient on maximum urate lowering therapy or where therapy cannot be escalated further due to intolerance/adverse reaction to either allopurinol or febuxostat.
- End stage renal failure/transplant
- Current prescription of medication known to interact with xanthine oxidase inhibitors such as azathioprine or mercapto-purine.
The study team makes the final eligibility decision.
Where it's taking place
- Edinburgh, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 2 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Edinburgh, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.