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Compares treatment options for Severe Aortic Stenosis
Official title Aspirin vs Clopidogrel After TAVR
ClinicalTrials.gov ID: NCT05493657
What this study is testing
What is Aspirin single antiplatelet therapy?
Aspirin single antiplatelet therapy is an investigational medicine, being studied as a potential treatment for severe aortic stenosis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Currently, the optimal antithrombotic therapy after transcatheter aortic valve replacement (TAVR) remains still unknown., The purpose of the study is to compare aspirin versus clopidogrel monoantiplatelet therapy for preventive effect on leaflet thrombosis in patients undergoing TAVR for severe aortic stenosis. This study is designed as a prospective, multicenter, open label, randomized controlled study.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 and older
You may be able to join if
- Patients \>19 years old
- Patients who underwent TAVR symptomatic severe AS
- Provision of informed consent
You likely can't join if
- Patients requiring dual antiplatelet therapy longer than 4 weeks
- Any conditions requiring specific antiplatelet therapy aspirin or clopidogrel
- History of stroke or transient ischemic attack (TIA) within 6 months
- Planned major surgery
- Cardiogenic shock or hemodynamic instability
- Chronic kidney disease stage 4 or 5 (eGFR \<30mL/min)
See the full eligibility criteria
- Patients \>19 years old
- Patients who underwent TAVR symptomatic severe AS
- Provision of informed consent
- Patients requiring dual antiplatelet therapy longer than 4 weeks
- Any conditions requiring specific antiplatelet therapy aspirin or clopidogrel
- History of stroke or transient ischemic attack (TIA) within 6 months
- Planned major surgery
- Cardiogenic shock or hemodynamic instability
- Chronic kidney disease stage 4 or 5 (eGFR \<30mL/min)
- Valve-in-valve TAVR procedure
- Hypersensitivity or contraindication to aspirin or clopidogrel
- Indication for anticoagulation therapy
The study team makes the final eligibility decision.
Where it's taking place
- Seoul, South Korea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Seoul, South Korea. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.