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New treatment option for MDR-TB
Official title A Exploratory Study of Vγ2Vδ2 T Lymphocyte-based Immunotherapy for MDR-TB
ClinicalTrials.gov ID: NCT05493267
What this study is testing
What is Vγ2Vδ2 T lymphocyte-based immunotherapy?
Vγ2Vδ2 T lymphocyte-based immunotherapy is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for mdr-tb.
Also referred to as Drug combination (zoledronic acid/interleukin 2).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- A Exploratory Study of drug combination (zoledronic acid/interleukin 2) that specifically amplifies Vγ2Vδ2 T cells in combination with anti-tuberculosis chemotherapy for the treatment of MDR-TB.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- RR-TB/MDR-TB (resistant to at least isoniazid and rifampicin).
- Poor how well it works of the original treatment regimen or no response to treatment or less than 4 effective drugs.
You likely can't join if
- Immunosuppression due to co-morbidities, such as immune system disorders, tumors, etc.
- Test confirms poor response to ZOL and IL-2 stimulation.
The study team makes the final eligibility decision.
Where it's taking place
- Shanghai, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shanghai, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.