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New treatment option for Peri-Implantitis
Official title The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis
ClinicalTrials.gov ID: NCT05415111
What this study is testing
- What it's testing
- The key objective of the study is to compare the effects of soft tissue augmentation using a volume stable collagen matrix or autogenous connective tissue graft or no soft tissue augmentation in addition to bone grafting/implantoplasty in patients who undergo surgical therapy of peri-implantitis with respect to clinical resolution of the infection.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Age \> 18 years old (UZH, FRA) or \> 21 years old (SIN), male and female.
- Diagnosed with periimplantitis of at least 1 implant in function for at least 1 year Diagnostic criteria
- Presence of bleeding and/or suppuration on gentle probing.
- Probing depths of ≥6 mm.
- Bone levels ≥3 mm apical of the most coronal portion of the intraosseous part of the implant.
You likely can't join if
- Pregnant or lactating female patient at inclusion
- Allergy or objection to porcine and bovine implantable biomaterials
- Allergy to Penicillin or NSAIDs
- Known or suspected non-compliance, drug or alcohol abuse
- Inability to follow the procedures of the study, e.g. due to language/ comprehension problems, psychological disorders, dementia, etc. of the...
- Smoking \> 15 cigarettes a day
See the full eligibility criteria
- Age \> 18 years old (UZH, FRA) or \> 21 years old (SIN), male and female.
- Diagnosed with periimplantitis of at least 1 implant in function for at least 1 year Diagnostic criteria
- Presence of bleeding and/or suppuration on gentle probing.
- Probing depths of ≥6 mm.
- Bone levels ≥3 mm apical of the most coronal portion of the intraosseous part of the implant.
- Periodontal health (including previously treated periodontitis patients with reduced but healthy periodontium)
- Good oral hygiene (full mouth plaque score \<25%)
- Adequate control of inflammation (full mouth BOP \<25%)
- Signed informed consent form
- Pregnant or lactating female patient at inclusion
- Allergy or objection to porcine and bovine implantable biomaterials
- Allergy to Penicillin or NSAIDs
- Known or suspected non-compliance, drug or alcohol abuse
- Inability to follow the procedures of the study, e.g. due to language/ comprehension problems, psychological disorders, dementia, etc. of the participant
- Smoking \> 15 cigarettes a day
- Active periodontal disease
The study team makes the final eligibility decision.
Where it's taking place
- Frankfurt, Germany
- Singapore, Singapore
- Zurich, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Frankfurt, Germany; Singapore, Singapore; Zurich, Switzerland. Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.