BridgeMD
New treatment option for Duchenne Muscular Dystrophy
Official title Once Weekly Infant Corticosteroid Trial for DMD
ClinicalTrials.gov ID: NCT05412394
What this study is testing
What is Prednisolone?
Prednisolone is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for duchenne muscular dystrophy.
Also referred to as Corticosteroid.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg/kg/week) will be equally effective to the 10mg/kg/week dose.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 1 to 30, men only
You may be able to join if
- people ages 1 month through 30 months
- Weakness consistent with Duchenne on exam, creatine kinase ≥ 20 times the upper limit of normal, and genetic mutation known to be causative for DMD.
You likely can't join if
- Prior treatment with Glucocorticosteroids
The study team makes the final eligibility decision.
Where it's taking place
- Chicago, Illinois, United States
- Cincinnati, Ohio, United States
- Columbus, Ohio, United States
- Dallas, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 1 month to 30 months. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chicago, Illinois, United States; Cincinnati, Ohio, United States; Columbus, Ohio, United States; Dallas, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.