BridgeMD
New treatment option for Amblyopia
Official title Optical Correction and Visual Functions of Adults With Amblyopia
ClinicalTrials.gov ID: NCT05394987
What this study is testing
- What it's testing
- Amblyopia is a developmental anomaly resulting from abnormal visual experiences in early life. Amblyopia causes reduced visual acuity in the absence of a pathology.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 39. Healthy volunteers may be eligible.
You may be able to join if
- 18-39 (inclusive) years of age
- Anisometropic amblyopia (difference of ≥0.50D spherical equivalent or ≥1.50D astigmatism between eyes) or mixed mechanism amblyopia (strabismus and...
- Best corrected visual acuity (BCVA) in the amblyopic eye of 0.3 logMAR to 1.0 logMAR (inclusive)
- BCVA in the non-amblyopic eye of 0.1 logMAR or better, and an interocular VA difference of 2 logMAR lines or more
- Difference of 1.00D or more between current refractive correction and study prescription
You likely can't join if
- Other pathological ocular anomalies known to cause reduced visual acuity
- Presbyopia (based on amplitude of accommodation)
- Inability to tolerate prescribed refractive correction in spectacles (e.g., due to aniseikonia)
- Contraindication to cycloplegic eye drops
- Currently under amblyopia treatment/therapy
- Inability to comprehend test instructions and/or provide consent
See the full eligibility criteria
- 18-39 (inclusive) years of age
- Anisometropic amblyopia (difference of ≥0.50D spherical equivalent or ≥1.50D astigmatism between eyes) or mixed mechanism amblyopia (strabismus and anisometropia)
- Best corrected visual acuity (BCVA) in the amblyopic eye of 0.3 logMAR to 1.0 logMAR (inclusive)
- BCVA in the non-amblyopic eye of 0.1 logMAR or better, and an interocular VA difference of 2 logMAR lines or more
- Difference of 1.00D or more between current refractive correction and study prescription
- Good general health
- Other pathological ocular anomalies known to cause reduced visual acuity
- Presbyopia (based on amplitude of accommodation)
- Inability to tolerate prescribed refractive correction in spectacles (e.g., due to aniseikonia)
- Contraindication to cycloplegic eye drops
- Currently under amblyopia treatment/therapy
- Inability to comprehend test instructions and/or provide consent
- Eccentric fixation
- \>-6.00DS of myopia in either eye with spectacles
- Bilateral amblyopia
- Presence of amblyopia that is not due to strabismus and/or anisometropia
- Presence of (current or previous) psychiatric, visual, or neurological disorders
The study team makes the final eligibility decision.
Where it's taking place
- Waterloo, Ontario, Canada
- Hong Kong, Guangdong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 39 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Waterloo, Ontario, Canada; Hong Kong, Guangdong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.