BridgeMD
New treatment option for Endothelial Dysfunction
Official title Sodium Lowering Vascular Effects Trial
ClinicalTrials.gov ID: NCT05388032
What this study is testing
- What it's testing
- The proposed mechanistic trial will test the effect of dietary sodium reduction on cardiac and vascular structure and function in those with elevated blood pressure or hypertension. Findings from this study will fill the knowledge gap on the underlying mechanisms of dietary sodium intake on cardiovascular disease risk in addition to blood pressure and could provide further evidence on sodium reduction for the prevention of cardiovascular disease.
- Time commitment: about 12 months
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- Men or women aged ≥40 years. Individuals \<40 years are at a low risk for clinical and subclinical CVD
- Elevated BP or hypertension (systolic BP ≥120 mmHg and diastolic BP ≥80 mmHg with or without use of antihypertensive medications)
You likely can't join if
- Glomerular filtration rate (eGFR) \<30 or end-stage renal disease (kidney transplant or chronic dialysis)
- History of cardiovascular disease
- Shift worker or regularly work at night
- Cancer requiring chemotherapy or radiation treatment in the previous two years
- Current pregnancy or breastfeeding or plans to become pregnant during the study
- Consumption of ≥21 alcoholic drinks/week
See the full eligibility criteria
- Men or women aged ≥40 years. Individuals \<40 years are at a low risk for clinical and subclinical CVD
- Elevated BP or hypertension (systolic BP ≥120 mmHg and diastolic BP ≥80 mmHg with or without use of antihypertensive medications)
- Glomerular filtration rate (eGFR) \<30 or end-stage renal disease (kidney transplant or chronic dialysis)
- History of cardiovascular disease
- Shift worker or regularly work at night
- Cancer requiring chemotherapy or radiation treatment in the previous two years
- Current pregnancy or breastfeeding or plans to become pregnant during the study
- Consumption of ≥21 alcoholic drinks/week
- Current participation in another lifestyle intervention or drug trial
- Current residence or planned residence that makes it difficult to meet trial requirements
- Other concerns regarding ability to meet trial requirements (at the discretion of the study coordinator)
The study team makes the final eligibility decision.
Where it's taking place
- New Orleans, Louisiana, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 12 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New Orleans, Louisiana, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.