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New treatment option for Sedation Complication
Official title Pharmacokinetics-pharmacodynamics of Morphine With or Without Midazolam Administered by Continuous Infusion in Neonatal Intensive Care
ClinicalTrials.gov ID: NCT05371886
What this study is testing
- What it's testing
- This study aims to describe a dose-effect relationship of morphine alone and morphine and midazolam administered as continuous infusion in neonates hospitalized in Neonatal intensive care unit and undergoing mechanical ventilation, through PKPD modelling.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 45
You may be able to join if
- Neonates \< 45 weeks of corrected gestational age
- Hospitalized in a Neonatal Intensive Care Unit
- Undergoing mechanical ventilation
- Patients that receive morphine alone or morphine and midazolam as continuous infusion
- Affiliated to a social security system
You likely can't join if
- Current weight \< 600g
- Neonates under palliative care
- Therapeutic hypothermia for perinatal anoxia
- Neonates who underwent a surgical procedure during the past 72 hours
- Neonates receiving concomitantly a paralytic or another drug for sedation or analgesia other than morphine or midazolam (except for...
- Parents refusing that their child participate
The study team makes the final eligibility decision.
Where it's taking place
- Brest, France
- Corbeil-Essonnes, France
- Créteil, France
- Lille, France
- Tours, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 weeks to 45 weeks. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Brest, France; Corbeil-Essonnes, France; Créteil, France; Lille, France; Tours, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.