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New treatment option for Pain, Postoperative
Official title Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery
ClinicalTrials.gov ID: NCT05351229
What this study is testing
What is Morphine Sulfate?
Morphine Sulfate is an investigational medicine, being studied as a potential treatment for pain, postoperative.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- VATS/RATS is widely used for diagnosis and treatment of intrathoracic conditions. Despite many benefits, postoperative pain continues to be intense after VATS/RATS.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Age 18-80 years old
- Undergoing elective video-assisted thoracoscopic or robotic assisted surgery for anatomical lung resection
- General anesthesia with anticipated intraoperative extubation.
You likely can't join if
- American Society of Anesthesiologists (ASA) classification of 4 or 5
- Anticipated postoperative intubation
- Significant liver disease
- Preoperative use of intravenous inotropes and/or vasopressor support
- Preoperative mechanical ventilation
- Preoperative use of mechanical circulatory support device (intraaortic balloon pump, ventricular assist device, extracorporeal membrane oxygenation)
See the full eligibility criteria
- Age 18-80 years old
- Undergoing elective video-assisted thoracoscopic or robotic assisted surgery for anatomical lung resection
- General anesthesia with anticipated intraoperative extubation.
- American Society of Anesthesiologists (ASA) classification of 4 or 5
- Anticipated postoperative intubation
- Significant liver disease
- Preoperative use of intravenous inotropes and/or vasopressor support
- Preoperative mechanical ventilation
- Preoperative use of mechanical circulatory support device (intraaortic balloon pump, ventricular assist device, extracorporeal membrane oxygenation)
- Severe pulmonary disease (home oxygen requirement and/or current oral steroid use)
- Morphine allergy
- Opioid or alcohol abuse
- Chronic pain
- Renal failure
- Inability to comprehend English language
- Bleeding disorder
- Abnormal preoperative coagulation
- Infection
- Patient refusal
- Failed spinal
The study team makes the final eligibility decision.
Where it's taking place
- Chicago, Illinois, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chicago, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.