BridgeMD
New treatment option for Spinal Cord Injuries
Official title Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
ClinicalTrials.gov ID: NCT05337982
What this study is testing
- What it's testing
- The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI). The investigators will test conditions in the blood and spinal fluid to determine the best time to start this new training program.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85. Healthy volunteers may be eligible.
You may be able to join if
- SCI participants WITHIN 1-5 MONTHS OF THEIR INJURY:
- Discharged from inpatient rehabilitation;
- AIS A-D at neurologic level C1-T10;
- 18-85 years old. Healthy controls:
- Adults 18-85 years old;
You likely can't join if
- SCI participants:
- Use of botox in the past 3 months that reduces skeletal muscle function;
- other neurologic conditions (i.e. brain injury, stroke, HIV);
- current cancer diagnosis;
- active deep vein thrombosis and anti-coagulation therapy;
- skin wounds in regions that interfere with harness, stimulation pads or hand placement needed for training.
See the full eligibility criteria
- SCI participants WITHIN 1-5 MONTHS OF THEIR INJURY:
- Discharged from inpatient rehabilitation;
- AIS A-D at neurologic level C1-T10;
- 18-85 years old. Healthy controls:
- Adults 18-85 years old;
- no recent major musculoskeletal injury;
- no recent surgery.
- SCI participants:
- Use of botox in the past 3 months that reduces skeletal muscle function;
- other neurologic conditions (i.e. brain injury, stroke, HIV);
- current cancer diagnosis;
- active deep vein thrombosis and anti-coagulation therapy;
- skin wounds in regions that interfere with harness, stimulation pads or hand placement needed for training.
- pregnancy;
- ventilator-dependence;
- cognitive conditions that preclude providing informed consent.
- Implanted medical devices that are contraindicated for electrical stimulation or MRI \ (If SCI participants have conditions contraindicated for MRI they may still participate in the remainder of study activities without...
- Implanted medical devices that are contraindicated for MRI (MRI participants only);
- neurologic conditions (i.e. brain injury, stroke, HIV);
- current cancer diagnosis;
- clotting disorders requiring anti-coagulation therapy;
- inflammatory conditions like arthritis, ulcerative colitis, lupus, etc;
- pregnancy;
- fear of needles;
- claustrophobia;
- cognitive conditions that preclude providing informed consent.
The study team makes the final eligibility decision.
Where it's taking place
- Columbus, Ohio, United States
- Vancouver, Canada
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Columbus, Ohio, United States; Vancouver, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.