BridgeMD
New treatment option for Post Traumatic Stress Disorder
Official title Effect of Attentional Therapy on Post-traumatic Stress Disorder
ClinicalTrials.gov ID: NCT05331534
What this study is testing
- What it's testing
- Post-traumatic stress disorder (PTSD) is associated with an attentional bias towards negative stimuli, which is supposed to contribute to the development and the maintenance of the disorder. We recently showed using eye-tracking evidenced two types of AB towards negative stimuli: a "physiological AB" found both in healthy and individual with PTSD, characterized by a stronger initial attentional engagement towards negative stimuli compared to neutral stimuli, as revealed by longer first fixation duration dwell time on negative pictures than on neutral pictures; a "pathological bias" observed only in individuals with PTSD and characterized by an heightened sustained attention towards negative stimuli once detected, which further increases with prolonged exposure.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Understanding and able to express themselves in French
- Giving informed consent, by dating and signing the study participation form
- Having health insurance coverage
- Normal or corrected to normal vision and hearing
- DSM-5 PTSD criteria, assessed using the CAPS and PCL-5
You likely can't join if
- Minors or adults under guardianship, under judicial protection, persons deprived of liberty
- Pregnant or breastfeeding women
- Refusal to participate after being clearly and fairly informed about the study
- Sensory, visual or auditory incapacity to participate in the study
- Personal history of neurological disorder or current neurological disorder
- Use of drugs other than tobacco and alcohol
See the full eligibility criteria
- Understanding and able to express themselves in French
- Giving informed consent, by dating and signing the study participation form
- Having health insurance coverage
- Normal or corrected to normal vision and hearing
- DSM-5 PTSD criteria, assessed using the CAPS and PCL-5
- Minors or adults under guardianship, under judicial protection, persons deprived of liberty
- Pregnant or breastfeeding women
- Refusal to participate after being clearly and fairly informed about the study
- Sensory, visual or auditory incapacity to participate in the study
- Personal history of neurological disorder or current neurological disorder
- Use of drugs other than tobacco and alcohol
- Alcohol use on the day of experimentation
- Personal history of psychiatric disorders or current psychiatric disorders other than anxiety, depressive, or trauma and stress disorders assessed at clinical interview and with MINI
- Personal history of multiple trauma in childhood
- Psychotropic medication treatment not stabilized over the past 4 weeks
- MOCA \< 26
- Contraindication to prolonged exposure therapy
The study team makes the final eligibility decision.
Where it's taking place
- Lille, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lille, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.